Manufacturer: Synokem Pharmaceuticals Ltd
Salt Composition : Progesterone(Natural Micronized)(300mg)
Cynthogest 300mg Tablet SR is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well. The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently.
Cynthogest 300mg Tablet SR is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.
The “classical” mechanism by which progesterone elicits its effects is via the progesterone receptor (PR), which, like the estrogen receptor (ER), has classically been described as a nuclear transcription factor, acting through specific progesterone response elements (PRE) within the promoter region of target genes
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cynthogest
Hot flushes
Serve side effects of Cynthogest
Abdominal pain
Sleepiness
Absence of menstrual periods
Itching
Flatulence
Nausea
Depression
Breast tenderness
Abnormal vaginal bleeding
Altered menstrual cycle
Edema (swelling)
Change in body weight
Changes in cervical secretion
Cholestatic jaundice
Injection site reactions (pain, swelling, redness)
Red spots or bumps
Acne
Hair loss
Excessive hair growth on face
Anaphylactic reaction
Fever
Insomnia (difficulty in sleeping)
Soreness
Diarrhea
Vaginal irritation
Vaginal dryness
Dementia
Deep vein thrombosis (blood clot in the legs)
Myocardial infarction
Stroke
Pulmonary embolism
Breast cancer
Allergy.
Abnormal Vaginal Bleeding.
Breast Cancer.
Miscarriage.
Heart And Blood Vessel Disorder.
Liver Disease.
This medicine is not recommended for use if you are pregnant or are suspecting a pregnancy.
Cynthogest 300mg Tablet SR is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
It is not known whether it is safe to consume alcohol with Cynthogest 300mg Tablet SR. Please consult your doctor.
Cynthogest 300mg Tablet SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Progesterone (Natural Micronized) is used for hormone replacement therapy and female infertility. It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
PROGESTERONE (NATURAL MICRONIZED) may have an interaction with medicines including anticonvulsants (acetazolamide, and carbamazepine), anti-infectives (metronidazole, clindamycin), antidepressants (fluoxetine, paroxetine, sertraline) or herbal preparation (Ginkgo Biloba).
Do not chew, crush or break it. Cynthogest 300mg Tablet SR is to be taken with food.
Store below 30°C
If you miss a dose of Cynthogest 300mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Cynthogest 300mg Tablet SR is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
It is used as a part of hormone replacement therapy generally in combination with an estrogen.
It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
It should be taken with food.
It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cynthogest 300mg Tablet SR is to be taken with food.
Q. What is Cynthogest 300mg Tablet SR?
Cynthogest 300mg Tablet SR is a type of progesterone hormone which is extracted from plants, but its property matches with the human progesterone. This medicine undergoes a process called micronization where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Cynthogest 300mg Tablet SR in the body and decreases its side effects.
Q. What is Cynthogest 300mg Tablet SR used to treat?
Cynthogest 300mg Tablet SR is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.
Q. Can you take Cynthogest 300mg Tablet SR every day?
Yes, Cynthogest 300mg Tablet SR can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.
Q. Does Cynthogest 300mg Tablet SR cause weight gain?
Yes, taking Cynthogest 300mg Tablet SR may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Cynthogest 300mg Tablet SR is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.
Q. Is Cynthogest 300mg Tablet SR safe?
Yes, Cynthogest 300mg Tablet SR is safer as compared to the normal synthetic progesterone. Its smaller size helps the body absorb it easily and reduces the side effects like fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance.
Q. How is progesterone beneficial for fertility and pregnancy?
Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Cynthogest 300mg Tablet SR (natural micronized form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.
