Cytalon 500mg Injection (1ml)

Manufacturer: Celon Laboratories Ltd

Salt Composition : Cytarabine(500mg)


Cytalon 500 Injection is given as an injection into the vein or under skin by the healthcare professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

The sugar moiety of cytarabine hinders the rotation of the molecule within the DNA. The DNA replication ceases, specifically during the S phase of the cell cycle, making it a specific drug for rapidly dividing cells, such as those seen in cancer

Pharmacokinets

As cytarabine is an S-phase-specific drug, prolonged exposure of cells to cytotoxic concentrations is critical to achieve maximum cytotoxic activity. However, the activity of cytarabine is decreased by its rapid deamination to the biologically inactive metabolite uracil arabinoside.


Side Effects

Rash

Skin ulcer

Nausea

Vomiting

Hair loss

Abdominal pain

Anal ulcers

Anemia (low number of red blood cells)

Decreased white blood cell count

Fever

Infection

Abnormal liver function

Low blood platelets

Mouth ulcer

Pneumonia

Sepsis

Mouth sore

Stomatitis (Inflammation of the mouth)


Contra Indications

Cytarabine is contraindicated in patients who have had a hypersensitivity reaction to it or any of the fundamental ingredients used in the preparation of the drug. With active meningeal infections, liposomal cytarabine is also contraindicated

Pregnancy Related Information

Cytalon 500 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Cytalon 500 Injection. Please consult your doctor.


Breast Feeding Related Information

Cytalon 500 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Labeled indications of cytarabine include the treatment of acute lymphoblastic leukemia, remission induction therapy in acute myeloid leukemia in adult and pediatric patients, the treatment of chronic myeloid leukemia (blast phase), and prophylaxis and treatment of meningeal leukemia

Interactions

infections.

myelosuppression.

hepatic dysfunction.

renal dysfunction.


Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Cytalon 500 Injection a vesicant?

No. Cytalon 500 Injection is not a vesicant (irritant) but should be handled with care.

Q. Is Cytalon 500 Injection ototoxic?

No. Ototoxicity is not reported with use of Cytalon 500 Injection. However, please consult your doctor if you experience such a side effect.

Q. Is Cytalon 500 Injection cytotoxic?

Yes. Cytalon 500 Injection is a cytotoxic drug.

Q. Does Cytalon 500 Injection cause hair loss?

Yes. Cytalon 500 Injection may cause hair loss.