Manufacturer: Cipla Ltd
Salt Composition : Vincristine(1mg)
Vial of 1ml Injection
(Inclusive of all taxes)
Cytocristin 1mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
The mechanism of action of vincristine sulfate has been related to the inhibition of microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. Central nervous system leukemia has been reported in patients undergoing otherwise successful therapy with vincristine sulfate
Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Hair loss
Peripheral neuropathy (tingling and numbness of feet and hand)
Constipation
anemia.
decreased blood platelets.
low levels of a type of white blood cell called neutrophils.
Charcot-Marie-Tooth disease.
generalized disorder of peripheral nerves.
a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.
Cytocristin 1mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Cytocristin 1mg Injection. Please consult your doctor.
Cytocristin 1mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
The FDA-approved indications of vincristine are acute lymphocytic leukemia, lymphoid blast crisis of chronic myeloid leukemia, and Hodgkin and Non-Hodgkin lymphoma
Some products that may interact with this drug include: digoxin, phenytoin, drugs that may cause nerve damage to the ear (such as chemotherapy drugs that contain platinum), drugs that may cause difficult urination (including belladonna alkaloids, anticholinergic drugs such as atropine, antispasmodics
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
Consult a doctor before taking any medicines
Cytocristin 1mg Injection is given as a drip in the vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
