Manufacturer: Cipla Ltd
Salt Composition : Vincristine(1mg)
Vial of 1ml Injection
(Inclusive of all taxes)
Cytocristin Aqueous 1mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
Vincristine belongs to a group of drugs known as the vinca alkaloids. Vinca alkaloids are organic compounds made up of carbon, hydrogen, nitrogen, and oxygen derived from the periwinkle plant. These drugs block cell growth by stopping mitosis by interfering with microtubule polymerization.
Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cytocristin
Hair loss
Peripheral neuropathy (tingling and numbness of feet and hand)
Constipation
anemia.
decreased blood platelets.
low levels of a type of white blood cell called neutrophils.
Charcot-Marie-Tooth disease.
generalized disorder of peripheral nerves.
a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.
Cytocristin Aqueous 1mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Cytocristin Aqueous 1mg Injection. Please consult your doctor.
Cytocristin Aqueous 1mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
The FDA-approved indications of vincristine are acute lymphocytic leukemia, lymphoid blast crisis of chronic myeloid leukemia, and Hodgkin and Non-Hodgkin lymphoma.
Some products that may interact with this drug include: digoxin, phenytoin, drugs that may cause nerve damage to the ear (such as chemotherapy drugs that contain platinum), drugs that may cause difficult urination (including belladonna alkaloids, anticholinergic drugs such as atropine.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
Cytocristin Aqueous 1mg Injection is given as a drip in the vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
