Manufacturer: Abbott
Salt Composition : Dabigatran Etexilate(150mg)
Dablexa 150 Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
Dabigatran is a potent, synthetic, reversible, non-peptide thrombin inhibitor. The inhibition of thrombin results in decreased formation of fibrin and reduces thrombin-stimulated platelet aggregation and thus prevents the formation of thrombi.
Dabigatran pharmacokinetics are dose proportional after single doses of 10 to 400 mg. Given twice daily, dabigatran's accumulation factor is approximately two. Elimination Dabigatran is eliminated primarily in the urine. Renal clearance of dabigatran is 80% of total clearance after intravenous administration
Nausea
Anemia (low number of red blood cells)
Gastrointestinal bleeding
Dyspepsia
Diarrhea
Abdominal pain
Nosebleeds
Skin bleeding
operation on the spine.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
a hemorrhage in the brain.
bleeding.
a patient who is producing milk and breastfeeding.
antiphospholipid antibody syndrome.
procedure to place indwelling epidural catheter.
Dablexa 150 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Dablexa 150 Capsule.
Dablexa 150 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Dabigatran is used to treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults and children 3 months of age and older who have been treated with an injectable anticoagulant ('blood thinner').
Some products that may interact with this drug include: mifepristone. Other medications can affect the removal of dabigatran from your body, which may affect how dabigatran works. Examples include cobicistat, cyclosporine, dronedarone, ketoconazole, rifampin, and St. John's wort, among others
Dablexa 150 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Dablexa 150 Capsule, please consult your doctor.
Consult a doctor before taking any medicines.
Take it as per dose and duration suggested by your doctor.
Dablexa 150 Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Dablexa 150 Capsule temporarily.
Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Dablexa 150 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. When should I take Dablexa 150 Capsule?
Mostly, Dablexa 150 Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours. If you miss a dose of Dablexa 150 Capsule then take it as soon as possible up to 6 hours prior to the next scheduled dose. However, skip the missed dose if your next dose is less than 6 hours away. Never take two doses of Dablexa 150 Capsule at the same time.
Q. Can I drink alcohol with Dablexa 150 Capsule?
Taking alcohol while taking Dablexa 150 Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
Q. Can Dablexa 150 Capsule cause hair loss?
As compared to other blood-thinning medications, Dablexa 150 Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Dablexa 150 Capsule. Consult your doctor if you face hair loss while taking Dablexa 150 Capsule to rule out any other causes of hair loss.
Q. When will I feel better after taking Dablexa 150 Capsule?
Dablexa 150 Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Dablexa 150 Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
