Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Dalfampridine(10mg)
Dalstep 10mg Tablet ER must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
The putative mechanism of action of dalfampridine is restoration of action potential conduction via blockade of an as yet uncharacterized subset of potassium channels in demyelinated axons
Pharmacokinetics in adults with MS similar to that reported in healthy adults. In adults 29–56 years of age with MS who received a single 10-mg dalfampridine extended-release tablet, mean peak plasma concentration was 25.23 ng/mL and was attained 3.92 hours after the dose
Urinary tract infection
Sleep disturbance
Dizziness
Headache
Nausea
Weakness
Back pain
Balance disorder (loss of balance)
Paresthesia (tingling or pricking sensation)
Throat irritation
Nasal irritation
Constipation
Indigestion
Throat pain
Dalfampridine is contraindicated for use in patients with moderate or severe renal impairment (CrCl 50 mL/minute or less), including patients with renal failure. Dalfampridine is substantially excreted by the kidney, and the seizure risk is greater with increased drug exposure
Dalstep 10mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Dalstep 10mg Tablet ER may cause excessive drowsiness with alcohol.
Dalstep 10mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AMPYRA (dalfampridine) is indicated as a treatment to improve walking in patients with multiple sclerosis (MS). This was demonstrated by an increase in walking speed
Bacitracin Bacitracin may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Baclofen Baclofen may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Do not chew, crush or break it. Dalstep 10mg Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Consult a doctor before taking any medicines
Dalstep 10mg Tablet ER helps improve walking in adults with multiple sclerosis.
It may take 2-6 weeks for the medicine to start working. Keep taking it as prescribed.
Do not chew, cut, or crush the tablet as that may results in releasing too much medicine in your body at once.
Inform your doctor if you have a history of seizures or kidney problems.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dalstep 10mg Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Q. How long will it take for Dalstep 10mg Tablet ER to start working?
Dalstep 10mg Tablet ER may take a few weeks to improve the condition. The effect of the medicine on a particular patient varies according to the severity of the condition and response of the patient. Hence, during treatment with Dalstep 10mg Tablet ER, patient should be monitored on a weekly basis. Do consult your doctor and follow the instructions as given by your doctor.
Q. Is Dalstep 10mg Tablet ER an immunosuppressant?
Dalstep 10mg Tablet ER is used in the therapy of multiple sclerosis. It acts by increasing the conduction in the damaged neurons by blocking potassium channels. The effect with this medicine can be seen with an increase in walking speed in treated patients.
Q. Who should not take Dalstep 10mg Tablet ER?
Patients with kidney problems, allergic to Dalstep 10mg Tablet ER, or who ever had an episode of seizure should not take Dalstep 10mg Tablet ER. You should consult your doctor before you start taking this medication.
Q. How should I store Dalstep 10mg Tablet ER?
Usually this medication is to be stored at 15ºC to 30ºC. The medicine should be stored in the original packaging in order to protect from light and moisture. Do not use the medicine after its expiry date. Keep the medicine out of the reach of children.
