Manufacturer: Zydus Cadila
Salt Composition : Ketoconazole(2% w/w), Zinc pyrithione(1% w/w)
Tube of 50gm Cream
(Inclusive of all taxes)
Danclear Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after application of the medicine. If it gets into your eyes, nose, or mouth rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine.
Danclear Cream is a combination of two antifungal medicines: Ketoconazole and Zinc pyrithione. It works by destroying the cell membrane of fungi that cause dandruff.
Ketoconazole is 83.7% plasma protein (mainly albumin) bound, and 15.3% is erythrocyte bound, resulting in only 1% of free drug. Animal studies indicate strong binding to the cytochrome P-450 mono-oxygenase complex. Extensive metabolism to inactive metabolites occurs, the products being mainly excreted in the faeces.Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. It mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Danclear
Application site reactions (burning, irritation, itching and redness)
If you are suffering from any of the following diseases, you should not take Ketoconazole + Zinc pyrithione unless your doctor advises you to do so -
Heart Disease
Diabetes
Calcium Deficiency
Potassium Deficiency
Liver Disease
Infections
Allergy
Danclear Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Information regarding the use of Danclear Cream during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
This medication is used to treat a certain skin condition (seborrheic dermatitis, a type of dandruff). In this condition, it is believed that a fungus (Malassezia furfur) infects the skin or scalp, resulting in dry, flaky skin (scales) on the scalp, face, ears, chest, or upper back.
If you use other drugs or over the counter products at the same time, the effects of Danclear Cream may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Danclear Cream may interact with the following drugs and products:
Abiraterone acetate
Alcohol
Alfentanil
Aliskiren
Alprazolam
Aluminium hydroxide and oxide
Amphotericin B
Aprepitant
Artesunate
Astemizole
Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Danclear Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Danclear Cream must be applied to the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Stop using Danclear Cream and inform your doctor if you notice any irritation or any other skin infection.
Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
