Manufacturer: Zydus Cadila
Salt Composition : Ketoconazole(2% w/v), Zinc pyrithione(1% w/v)
Bottle of 90ml Shampoo
(Inclusive of all taxes)
Danclear Shampoo is only meant for external use and should be used as advised by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need it will not clear your condition faster and may only increase the side effects. Make sure not to leave it on the scalp for more than 5 minutes. If it gets into your eyes, nose, or mouth rinse with water.
Danclear Shampoo is a combination of two antifungal medicines: Ketoconazole and Zinc pyrithione. It works by destroying the cell membrane of fungi that cause dandruff.
Ketoconazole is 83.7% plasma protein (mainly albumin) bound, and 15.3% is erythrocyte bound, resulting in only 1% of free drug. Animal studies indicate strong binding to the cytochrome P-450 mono-oxygenase complex. Extensive metabolism to inactive metabolites occurs, the products being mainly excreted in the faeces.Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. It mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Danclear
Application site reactions (burning, irritation, itching and redness)
If you are suffering from any of the following diseases, you should not take Ketoconazole + Zinc pyrithione unless your doctor advises you to do so -
Heart Disease
Diabetes
Calcium Deficiency
Potassium Deficiency
Liver Disease
Infections
Allergy
Danclear Shampoo may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Information regarding the use of Danclear Shampoo during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
This medication is used to treat a certain skin condition (seborrheic dermatitis, a type of dandruff). In this condition, it is believed that a fungus (Malassezia furfur) infects the skin or scalp, resulting in dry, flaky skin (scales) on the scalp, face, ears, chest, or upper back.
If you use other drugs or over the counter products at the same time, the effects of Danclear Shampoo may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Danclear Shampoo may interact with the following drugs and products:
Abiraterone acetate
Alcohol
Alfentanil
Aliskiren
Alprazolam
Aluminium hydroxide and oxide
Amphotericin B
Aprepitant
Artesunate
Astemizole
check the label for directions before use.
Store below 30°C
If you miss a dose of Danclear Shampoo, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Danclear Shampoo is used for the treatment and prevention of fungal infections of the scalp such as dandruff.
Leave the shampoo on for three to five minutes before rinsing.
Take care to avoid getting it in your eyes. If accidental exposure occurs, rinse immediately with plenty of water.
Your usual shampoo can be used as necessary between treatment with Danclear Shampoo.
Danclear Shampoo must be applied to the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Stop using Danclear Shampoo and inform your doctor if you notice any irritation or any other skin infection.
Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
Use it as advised by your doctor or check the label for directions before use.