Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd
Salt Composition : Dapsone(100mg)
Dapsone Tablet should be used in the dose and duration as advised by your doctor. It should be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.Some people may develop a skin rash and fever as the side effects of this medicine. Please consult your doctor if these side effects bother you or persist for a longer duration. Use caution while treating patients with hypersensitivity to sulfa drugs.
As an antimicrobial agent, dapsone is bacteriostatic in action. It inhibits the synthesis of dihydrofolic acid through by competing with para-aminobenzoic acid for the active site of dihydropteroate synthetase [35, 41], thus resembling the action of sulphonamides.
The elimination half-life of dapsone is about 30 hours. The drug shows linear pharmacokinetics within the therapeutic range and the time-course after oral administration fits a 2-compartment model. The concentration-time profile of dapsone after parenteral administration is reviewed.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dapsone
Rash
Fever
If you are suffering from any of the following diseases, you should not take Dapsone unless your doctor advises you to do so -
Liver Disease
Anemia
Allergy
Dapsone Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Dapsone Tablet. Please consult your doctor.
Dapsone Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Dapsone is indicated for a variety of conditions, both dermatologic and non-dermatologic. The FDA-approved indications are leprosy and dermatitis herpetiformis. The non-FDA-approved indications include a wide range of dermatoses and malaria and Pneumocystis (carinii) jiroveci prophylaxis and treatment.
aluminum hydroxide.
BCG vaccine live.
calcium carbonate.
famotidine.
idelalisib.
ivacaftor.
lansoprazole.
mefloquine.
Do not chew, crush or break it. Dapsone Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Dapsone Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
When used long term, your doctor may monitor amount of blood cells in your blood regularly.
Inform your doctor if your condition does not improve or you get eye or nerve problems.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dapsone Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Who should not use Dapsone Tablet?
Use of Dapsone Tablet should be avoided in patients who are allergic to Dapsone Tablet or any of its components. However, if you are not aware of any allergy or if you are using Dapsone Tablet for the first time, consult your doctor.
Q. Is Dapsone Tablet safe?
Dapsone Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. What if I forget to take a dose of Dapsone Tablet?
If you forget a dose of Dapsone Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. Can I stop taking Dapsone Tablet when I feel better?
No, do not stop taking Dapsone Tablet without consulting the doctor even if you feel better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration. Stopping Dapsone Tablet too early may cause symptoms to reoccur or worsen. Continue taking Dapsone Tablet in the dose and duration advised by the doctor.
Q. Can I take a higher than the recommended dose of this medicine?
No, Dapsone Tablet should be taken in the recommended dose only. Overdose of Dapsone Tablet can increase the risks of side effects. If you experience an increase in the severity of your symptoms while being on the prescribed dose, please consult your doctor for re-evaluation.
Q. What if I don't get better after using Dapsone Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using this medicine. The doctor may modify the dose or suggest an alternative medicine.
