Manufacturer: Wockhardt Ltd
Salt Composition : Darbepoetin alfa(40mcg)
Darbotin 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
Darbepoetin alfa is in a class of medications called erythropoiesis-stimulating agents (ESAs). It works by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.
A long terminal half-life characterizes the pharmacokinetic profile of darbepoetin alfa following both IV and SC administration. The most recent pharmacokinetic studies using sampling times of 27 or 28 days established that the mean terminal half-life of darbepoetin alfa is 70–105 h when administered SC
High blood pressure
Rash
Injection site pain
Breathlessness
Cough
Peripheral edema
Procedural hypotension (low blood pressure)
Convulsion
Thromboembolism
inadequate folic acid.
inadequate vitamin B12.
porphyria.
anemia from inadequate iron.
high blood pressure.
significant uncontrolled high blood pressure.
a heart attack.
a clot in the lung
Darbotin 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Darbotin 40 Injection. Please consult your doctor.
Darbotin 40 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Aranesp is indicated for the treatment of anemia in patients with non-myeloid malignancies where anemia is due to the effect of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy
belzutifan.
benazepril.
C1 esterase inhibitor (human)
captopril.
carfilzomib.
conestat alfa.
cyclosporine.
enalapril.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Darbotin 40 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Darbotin 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Stop taking Darbotin 40 Injection and inform your doctor if you develop shortness of breath or skin rash.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How long does it take for Darbotin 40 Injection to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Darbotin 40 Injection. If you have any other concerns, consult your doctor.
Q. Is Darbotin 40 Injection safe to use?
Darbotin 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Darbotin 40 Injection therapy. Follow all the directions strictly.
Q. Other than PRCA, can there be other reasons for not responding to Darbotin 40 Injection?
You may not respond to Darbotin 40 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Q. Can Darbotin 40 Injection be used in children?
Yes, Darbotin 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Darbotin 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
