DECAPEPTYL DEPOT 3.75 MG INJECTION

Manufacturer: Ferring Pharmaceuticals

Salt Composition : Triptorelin(3.75mg)


Decapeptyl Depot Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

Triptorelin (trip" toe rel' in) is a decapeptide analogue of gonadotropin releasing hormone (GnRH) that acts on the pituitary to cause the synthesis and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH), two gonadotropins that act on the male testes to stimulate the production of testosterone

Pharmacokinets

The pharmacokinetics of triptorelin follows a 3 compartment model. The half lives are estimated to be 6 minutes, 45 minutes, and 3 hours respectively. In healthy male volunteers, total clearance of triptorelin was 211.9 mL/min.


Side Effects

Weakness

Increased sweating

Back pain

Paresthesia (tingling or pricking sensation)

Hot flashes

Erectile dysfunction

Contra Indications

amiodarone. triptorelin increases toxicity of amiodarone by QTc interval. Contraindicated. ...

anagrelide. triptorelin increases toxicity of anagrelide by QTc interval. Contraindicated. ...

dofetilide. triptorelin increases toxicity of dofetilide by QTc interval. Contraindicated

Pregnancy Related Information

Decapeptyl Depot Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Decapeptyl Depot Injection. Please consult your doctor.


Breast Feeding Related Information

Information regarding the use of Decapeptyl Depot Injection during breastfeeding is not available. Please consult your doctor.


Indications

Triptorelin is indicated for the palliative treatment of advanced prostate cancer.


Interactions

Chloroquine The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Chloroquine.

Chlorpheniramine The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Chlorpheniramine

Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Decapeptyl Depot Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Decapeptyl Depot Injection helps in the treatment of locally advanced or metastatic prostate cancer.

It is given as an injection either under the skin or into a muscle.

It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.

It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.

Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.

Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.

It may also be used to treat endometriosis and precocious puberty (premature puberty).

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.