Decitas 50mg Injection

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Decitabine(50mg)


Decitas Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Basic Information

Mechanism Of Action

Decitas Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Pharmacokinets

Decitabine interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Decitas

Nausea

Vomiting

Headache

Fever

Lung infection

Decreased white blood cell count (neutrophils)

Nosebleeds

Anemia (low number of red blood cells)

Low blood platelets

Diarrhea

Pneumonia

Contra Indications

Nausea.

Fever.

Lung infection.

Decreased white blood cell count (neutrophils)

Nosebleeds.

Anemia (low number of red blood cells)

Low blood platelets.

Diarrhea.

Pregnancy Related Information

Decitas Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Decitas Injection. Please consult your doctor.


Breast Feeding Related Information

Decitas Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Decitas Injection is used in the treatment of blood cancer called acute myeloid leukaemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.

Interactions

If you use other drugs or over the counter products at the same time, the effects of Decitas Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Decitas Injection may interact with the following drugs and products:

Dichlorphenamide

Ethotoin

Fingolimod

Hydroxyurea

Palifermin

Sipuleucel-t

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

take it as soon as possible. However, if it is almost time for

 your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Decitas Injection a vesicant?

Decitas Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Decitas Injection into the surrounding tissues from the site of administration) when injected.

Q. How effective is Decitas Injection?

The effectiveness of Decitas Injection depends upon several factors including the patient's clinical condition, number of treatment cycles etc. and may vary depending upon the individual response.

Q. Does Decitas Injection cause hair loss?

Yes. Hair loss (alopecia) is among the known side effects of Decitas Injection.

Q. How is Decitas Injection administered?

Decitas Injection comes as a powder to be to be added to fluid and injected slowly over 3 hours into a vein (slow i.v infusion) by a doctor who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.