Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Salt Composition : Tamsulosin(0.4mg), Deflazacort(30mg)
Defcort TM Tablet may be prescribed alone or in combination with other medicines. It is best taken with food. Take it regularly and do not take more or use it for a longer duration than recommended by your doctor. You should not stop taking the medicine until your doctor tells you it is okay to stop.
Deflazacort is a corticosteroid prodrug, whose active metabolite, 21-desDFZ, acts through the glucocorticoid receptor to exert anti-inflammatory and immunosuppressive effects. The precise mechanism by which deflazacort exerts its therapeutic effects in patients with DMD is unknown.
Tamsulosin is in a class of medications called alpha blockers. It works by relaxing the muscles in the prostate and bladder so that urine can flow easily
Deflazacort is rapidly absorbed after oral administration with peak concentration occurring within 1-2 hours. One pharmacokinetic study determined an AUC (area under the curve) of 280 ng/ml · h. The bioavailability of both the oral suspension and tablet are similar
Tamsulosin exhibits high plasma-protein binding, largely to alpha(1)-acid glycoprotein. It is metabolized, mainly by cytochrome P450 (CYP) 3A4 and CYP2D6 to compounds with low abundance, and 8.7-15% of an oral dose is excreted renally as the parent compound
Runny nose
Ejaculation disorder
Dizziness
EMFLAZA is contraindicated in patients with known hypersensitivity to deflazacort or to any of the inactive ingredients. Instances of hypersensitivity, including anaphylaxis, have occurred in patients receiving corticosteroid therapy
Sulfonamide hypersensitivity. Tamsulosin is a non-arylamine sulfonamide derivative. ...
Orthostatic hypotension, renal failure, renal impairment, syncope. ...
Prostate cancer. ...
Hepatic disease. ...
Pregnancy. ...
Breast-feeding. ...
Children, infants. ...
Ocular surgery.
Information regarding the use of Defcort TM Tablet during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Defcort TM Tablet.
Information regarding the use of Defcort TM Tablet during breastfeeding is not available. Please consult your doctor.
Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids.
Tamsulosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency
Cisatracurium The risk or severity of myopathy and weakness can be increased when Cisatracurium is combined with Deflazacort.
Cisplatin The therapeutic efficacy of Cisplatin can be decreased when used in combination with Deflazacort.
Acid-blocking drug. Taking cimetidine with tamsulosin can increase the levels of tamsulosin in your body.
Antibiotic.
Antidepressant (SSRI) .
Antifungal drugs.
Erectile dysfunction (ED) drugs.
Other benign prostatic hyperplasia drug.
Alpha blockers.
Do not chew, crush or break it. Defcort TM Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Defcort TM Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Defcort TM Tablet is prescribed for the treatment of kidney stones.
Take adequate water or fluids while taking this medicine to prevent kidney stones.
You can also include citric acid rich food in your diet like grapefruit, oranges, lemons, or limes to prevent kidney stones.
Inform your doctor if you have any kidney or heart disease or high potassium levels in your blood.
Defcort TM Tablet can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defcort TM Tablet is to be taken with food.
Q. Can the use of Defcort TM Tablet cause weight gain?
There are reports that suggest that the use of Defcort TM Tablet can lead to weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.
Q. Can Defcort TM Tablet cause a painful erection?
Yes, Defcort TM Tablet contains tamsulosin, which may very rarely cause a painful erection. If this occurs, contact your doctor immediately.
Q. Will a higher than the recommended doses of Defcort TM Tablet be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended dosage does not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
Q. What are the instructions for the storage and disposal of Defcort TM Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
