Manufacturer: Tablets India Limited
Salt Composition : Domperidone(30mg), Rabeprazole(20mg)
Strip of 10 Capsule
(Inclusive of all taxes)
Degurge DSR 30mg/20mg Capsule is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The DA2-receptor antagonist domperidone antagonizes the inhibitory effect of dopamine, resulting in stimulation of gastric muscle contraction. This provides a mechanism for the gastrokinetic effect of domperidone
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion
The pharmacokinetics of rabeprazole are characterized by high and consistent bioavailability, dose proportionality, extensive hepatic metabolism, and primarily urinary excretion of these metabolites. In addition, rabeprazole does not accumulate with repeated dosing
The absorption of domperidone was very rapid, with mean peak plasma concentration (Cmax) values of 18.8, 15.0, and 20.7 ng/mL attained at 0.9, 1.2, and 0.6 hours after the administration of base tablet, maleate tablet, and solution, respectively. The mean elimination half-life (t1/2) ranged from 12.6 to 16.0 hours
Diarrhea
Stomach pain
Dryness in mouth
Headache
Dizziness
Flatulence
Weakness
Flu-like symptoms
diarrhea from an infection with Clostridium difficile bacteria.
inadequate vitamin B12.
low amount of magnesium in the blood.
low amount of calcium in the blood.
liver problems.
a type of kidney inflammation called interstitial nephritis.
subacute cutaneous lupus erythematosus
with conditions where cardiac conduction is, or could be, impaired.
with underlying cardiac diseases such as congestive heart failure.
receiving other medications known to prolong QT interval or potent CYP3A4 inhibitors.
with severe hepatic impairment.
Degurge DSR 30mg/20mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Degurge DSR 30mg/20mg Capsule. Please consult your doctor.
Degurge DSR 30mg/20mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Rabeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach
Domepridone is indicated for the relief of the symptoms of nausea and vomiting. Domeperidone should be used at the lowest effective dose for the shortest duration necessary to control nausea and vomiting. It is recommended to take oral domperidone tablets before meals
atazanavir.
clopidogrel.
dasatinib.
delavirdine.
digoxin.
idelalisib.
indinavir.
itraconazole.
amiodarone.
antihistamines
antipsychotic medications
aprepitant.
atropine
Degurge DSR 30mg/20mg Capsule is to be taken empty stomach.
Store below 30°C
If you miss a dose of Degurge DSR 30mg/20mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Degurge DSR 30mg/20mg Capsule for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Take this medicine in the dose and duration as advised by your doctor. Degurge DSR 30mg/20mg Capsule is to be taken empty stomach.
Q. What is Degurge DSR 30mg/20mg Capsule?
Degurge DSR 30mg/20mg Capsule is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
Q. What are the contraindications of Degurge DSR 30mg/20mg Capsule?
The use of Degurge DSR 30mg/20mg Capsule is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Q. Can the use of Degurge DSR 30mg/20mg Capsule cause dry mouth?
Yes, the use of Degurge DSR 30mg/20mg Capsule can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Q. Can the use of Degurge DSR 30mg/20mg Capsule cause diarrhea?
Yes, the use of Degurge DSR 30mg/20mg Capsule can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.
