Manufacturer: Delcure Life Sciences
Salt Composition : Paracetamol/Acetaminophen(325mg), Tramadol(37.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Delpodol P 325mg/37.5mg Tablet can be taken with or without food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors
Analgesics can inhibit the sensation of pain by inhibiting transmission of non-nociceptive impulses along primary afferents or by altering the perception of pain
Tramadol modulates the descending pain pathways within the central nervous system through the binding of parent and M1 metabolite to μ-opioid receptors and the weak inhibition of the reuptake of norepinephrine and serotonin
Tramadol is rapidly distributed in the body; plasma protein binding is about 20%. Tramadol is mainly metabolised by O- and N-demethylation and by conjugation reactions forming glucuronides and sulfates. Tramadol and its metabolites are mainly excreted via the kidneys. The mean elimination half-life is about 6 hours
Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 30 minutes to 2 hours after ingestion. It is metabolised in the liver (90-95%) and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol.
Acetaminophen has a high oral bioavailability (88%), it is well absorbed and reaches the peak blood concentrations within 90 minutes after ingestion.
APAP is not widely bound to plasma proteins, and has a plasma half-life of 1.5–2.5 hours at the recommended doses
Nausea
Vomiting
Constipation
Weakness
Dizziness
Dryness in mouth
Sleepiness
If you are allergic to tramadol, paracetamol or similar medicines.
If you are suffering from any liver problem.
If you are suffering from epilepsy or fits which is not under control by your current treatment.
Delpodol P 325mg/37.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Delpodol P 325mg/37.5mg Tablet.
Delpodol P 325mg/37.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Tramadol/Paracetamol tablets are indicated for the symptomatic treatment of moderate to severe pain. The use of Tramadol/Paracetamol should be restricted to patients whose moderate to severe pain is considered to require a combination of tramadol and paracetamol
Tramadol should not be used in combination with MAO inhibitors or serotonin-precursors (such as L-tryptophan, oxitriptan) and should be used with caution in combination with other serotonergic drugs
Despite its frequent coadministration with other drugs and widespread use, very few clinically significant drug interactions have been documented with paracetamol. Drugs that alter gastric emptying can alter paracetamol pharmacokinetics, but this does not result in toxicity in therapeutic use.
Drug interactions of Tylenol include carbamazepine, isoniazid, rifampin, alcohol, cholestyramine, and warfarin. Tylenol is often used during pregnancy for short-term treatment of fever and minor pain during pregnancy.
Do not chew, crush or break it. Delpodol P 325mg/37.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Delpodol P 325mg/37.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Use only for severe acute pain for not more than 5 days.
Prolonged use may result in physical and psychological dependence even at recommended dosages.
It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
It is better to take with food to avoid an upset stomach.
Your doctor may adjust your dose if you have liver or kidney disease.
In case of overdose, tell your doctor immediately.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Delpodol P 325mg/37.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Is it safe to use Delpodol P 325mg/37.5mg Tablet?
Yes, Delpodol P 325mg/37.5mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, constipation, weakness, dizziness, dryness in the mouth, sleepiness and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medication.
Q. Can I stop taking the medication when my pain is relieved?
Delpodol P 325mg/37.5mg Tablet is usually recommended for short-term use and can be discontinued when your pain is relieved. However, it is advisable that it should be taken only as suggested by your doctor.
Q. Can the use of Delpodol P 325mg/37.5mg Tablet cause constipation?
Yes, the use of Delpodol P 325mg/37.5mg Tablet can cause constipation. To prevent constipation eat high-fiber foods like vegetables, fruits and cereals. Drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or take a short walk. Talk to your doctor about taking some medicines to treat constipation if this persists for a long time.
Q. Can the use of Delpodol P 325mg/37.5mg Tablet cause dizziness?
Yes, the use of Delpodol P 325mg/37.5mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.
