Manufacturer: Pfizer Ltd
Salt Composition : Amoxapine(50mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Demolox 50mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication. This medicine usually shows a quick response and provides fast relief from the symptoms.
The primary mechanism of action of amoxapine is through inhibition of presynaptic reuptake of norepinephrine; patients should not take it alongside other antidepressants or drugs which impart similar effects, such as MAO inhibitors
Amoxapine reached maximum levels of 67.4 +/- 35.8 ng/ml between 1 and 2 h after administration. The decline of amoxapine levels in plasma was biphasic. The mean elimination half-life was 9.8 +/- 2.6 h and the estimated first-pass loss ranged between
Increased heart rate
Blurred vision
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dryness in mouth
Abnormality of voluntary movements
Parkinsonism
Weight gain
Akathisia (inability to stay still)
Dystonia (involuntary muscle contractions)
Difficulty in urination
Constipation
Increased heart rate
Blurred vision
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dryness in mouth
Abnormality of voluntary movements
Parkinsonism
Weight gain
Akathisia (inability to stay still)
Dystonia (involuntary muscle contractions)
Difficulty in urination
Constipation
Demolox 50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Demolox 50mg Tablet may cause excessive drowsiness with alcohol.
Demolox 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Amoxapine (amoxapine (amoxapine tablets) tablets) is indicated for the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. It is indicated for depression accompanied by anxiety or agitation
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication
Do not chew, crush or break it. Demolox 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Demolox 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Demolox 50mg Tablet for the treatment of depression.
Drink plenty of fluids as it may cause dehydration and constipation.
Monitor your weight during the treatment as Demolox 50mg Tablet can cause weight gain and increased appetite.
It may cause sleepiness. Don't drive or do anything requiring concentration until you know how Demolox 50mg Tablet affects you.
Talk to your doctor if you notice sudden mood changes, unusual movements or develop suicidal thoughts.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Demolox 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Demolox 50mg Tablet used for?
Demolox 50mg Tablet is a medicine used to treat depression. It restores the balance of certain chemicals (neurotransmitters) in the brain that are responsible for depression along with anxiety or agitation. This helps to elevate the mood and enhances the behavior by creating a feeling of well being.
Q. What are the side effects of Demolox 50mg Tablet?
The common side effects of Demolox 50mg Tablet are an increased heart rate, orthostatic hypotension (sudden decrease in blood pressure on standing), dryness in mouth, abnormality of voluntary movements, weight gain, difficulty in urination and constipation. Please consult your doctor if any of these side effects worry you. The doctor will suggest ways to manage or prevent them.
Q. I feel better now, can I stop taking Demolox 50mg Tablet?
No, you should not stop taking Demolox 50mg Tablet without discussing it with your doctor even if you feel better. This is because if you stop taking it suddenly, your depression may come back and your symptoms may worsen. Your doctor will decide for how long you need to continue this medicine. Consult your doctor if any of the side effects bother you. If you have completed your course of treatment, your doctor may decrease your dose gradually before taking you off this medicine.
Q. Is there anything I need to be careful about while on therapy with Demolox 50mg Tablet?
Demolox 50mg Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might worsen the drowsiness. Let your doctor know if you have any problems with your liver or kidneys and if you are on any medicines or supplements. This is because medicines may have interactions with each other and cause allergic reactions that can sometimes be serious. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
