Manufacturer: Maneesh Pharmaceuticals Ltd
Salt Composition : Nimesulide(100mg), Paracetamol(500mg)
Bottle of 60ml Syrup
(Inclusive of all taxes)
Denim P 100 mg/500 mg Syrup should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Nimesulide is rapidly distributed and has an apparent volume of distribution ranging between 0.18 and 0.39 L/kg. It is extensively bound to albumin; the unbound fraction in plasma was 1%. The unbound fraction increased to 2 and 4% in patients with renal or hepatic insufficiency.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Nausea
Vomiting
Diarrhea
Increased liver enzymes
If you are allergic to nimesulide or paracetamol.
If you have problems with your liver or kidneys.
If you have flu, fever, chills and shivering.
If you have a history of liver damage induced by medicines like nimesulide.
If you had or have stomach bleeding, ulcer and inflammation of stomach lining.
If you have problems related to blood clotting, bleeding disorders.
If you have serious heart failure problems or heart-related disorders.
It should not be used in patients less than 12 years old, pregnant women or breastfeeding mothers.
Information regarding the use of Denim P 100 mg/500 mg Syrup during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Denim P 100 mg/500 mg Syrup.
Information regarding the use of Denim P 100 mg/500 mg Syrup during breastfeeding is not available. Please consult your doctor.
This medication is a non-steroidal anti-inflammatory drug, prescribed for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever
NIMESULIDE+PARACETAMOL is shown to interact with various drugs. Some of them include lithium, anticancer/antimetabolites (methotrexate), blood thinner or anticoagulant (warfarin, coumadin, aspirin), blood pressure or heart medicine, nausea medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophyllines, ephedrine), immune system affecting medicine (cyclosporine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of NIMESULIDE+PARACETAMOL and may alter its efficacy.
Measure it with a measuring cup and take it by mouth. Shake well before use. Denim P 100 mg/500 mg Syrup is to be taken with food.
Store below 30°C
If you miss a dose of Denim P 100 mg/500 mg Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Q. What is Denim P 100 mg/500 mg Syrup?
Denim P 100 mg/500 mg Syrup is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Q. Can I stop taking Denim P 100 mg/500 mg Syrup when my pain is relieved?
Denim P 100 mg/500 mg Syrup is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.
Q. Can the use of Denim P 100 mg/500 mg Syrup cause nausea and vomiting?
Yes, the use of Denim P 100 mg/500 mg Syrup can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. Are there any specific contraindications associated with the use of Denim P 100 mg/500 mg Syrup?
The use of Denim P 100 mg/500 mg Syrup is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
