Manufacturer: Pfizer Ltd
Salt Composition : Medroxyprogesterone acetate(150mg/ml)
Medroxyprogesterone subcutaneous injection is used for the treatment of endometriosis, a condition in which the endometrial tissue grows outside the uterus.
Medroxyprogesterone acetate (MPA) inhibits the production of gonadotropin, preventing follicular maturation and ovulation, which is responsible for it's ability to prevent pregnancy. This action also thins the endometrium. MPA reduces nuclear estrogen receptors and DNA synthesis in epithelial cells of the endometrium
Oral medroxyprogesterone acetate (MPA) has an absorption half life of 15-30min and a biological half life of 40-60 hours. Intramuscular MPA has an absorption half life of 0.86±0.30 days and an elimination half life of 24.03±21.74 days.
Weight gain
Depression
Hot flashes
Joint pain
Breast pain and tenderness
Loss of vision or blurred vision
Swelling of face, lips, eyelids, tongue, hands and feet
White vaginal discharge
Shortness of breath
Hair loss
Headache
Dizziness
Nausea and Vomiting
PROVERA is contraindicated in women with any of the following conditions: Undiagnosed abnormal genital bleeding. Known, suspected, or history of breast cancer. Known or suspected estrogen- or progesterone-dependent neoplasia.
This medicine is not recommended for use in pregnant women.
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before administering this medicine. Your doctor may prescribe an alternative medicine based on your clinical condition.
Medroxyprogesterone acetate (MPA) oral tablets are indicated to treat secondary amenorrhea, reduce the incidence of endometrial hyperplasia in postmenopausal women, and to treat abnormal uterine bleeding due to hormonal imbalance, not organic pathology
Some products that may interact with this drug include: aminoglutethimide, drugs affecting liver enzymes that remove medroxyprogesterone from your body
CONSULT YOUR DOCTOR
STORE BELOW 30 DEGREES C.
If an injection schedule is missed, inform your doctor immediately. Your doctor will give you further instructions about the changed dosing schedule.
Seek emergency medical treatment or contact the doctor in case of an overdose.
CONSULT YOUR DOCTOR