Manufacturer: Pacific Drugs & Chemicals
Salt Composition : Alprazolam(0.25mg), Imipramine(25mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Depsolam 0.25 mg/25 mg Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may cause withdrawal symptoms.
The exact mechanism of action of alprazolam is unknown. Benzodiazepines bind to gamma aminobutyric acid (GABA) receptors in the brain and enhance GABA-mediated synaptic inhibition; such actions may be responsible for the efficacy of alprazolam in anxiety disorder and panic disorder
Imipramine is a tricyclic antidepressant that has been used since the 1950s. Its primary mechanism of action is to inhibit the reuptake of serotonin and norepinephrine, thus elevating the levels of these neurotransmitters in the brain
Alprazolam has a mean plasma elimination half-life of 11.2 hours in healthy patients (range 6.3-26.9 hours). The mean half-life is 16.3 hours (range 9.0-26.9 hours) in the elderly, 21.8 hours (range 9.9-40.4 hours) in obese patients, and 19.7 hours (range 5.8-65.3 hours) in patients with alcoholic liver disease.
The mean elimination half-life for imipramine was significantly decreased in alcoholics (8.7 vs. 19.9 hours after intravenous infusion and 10.9 vs. 19.6 hours after oral administration; P less than 0.05). The mean elimination half-life for desipramine was decreased in alcoholics after intravenous infusion
Constipation
Difficulty in urination
Dryness in mouth
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Tiredness
Blurred vision
Increased heart rate
Uncoordinated body movements
Depression
Memory impairment
overweight.
suicidal thoughts.
alcohol intoxication.
drug abuse.
depression.
wide-angle glaucoma.
closed angle glaucoma.
asthma.
overactive thyroid gland.
schizophrenia.
manic-depression.
suicidal thoughts.
alcoholism.
alcohol intoxication.
serotonin syndrome, a type of disorder with high serotonin levels.
increased pressure in the eye.
Depsolam 0.25 mg/25 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Depsolam 0.25 mg/25 mg Tablet.
Depsolam 0.25 mg/25 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alprazolam is frequently prescribed to manage panic and anxiety disorders. Alprazolam has also been misused for recreational purposes because of its disinhibition, euphoria, and anxiolytic effects. FDA-labeled indications include anxiety disorders and panic disorders with or without agoraphobia
Imipramine may be used to treat depression and nocturnal enuresis in children Label. Unlabeled indications include chronic and neuropathic pain (including diabetic neuropathy), panic disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder
carbamazepine.
cimetidine.
clarithromycin.
erythromycin base.
erythromycin ethylsuccinate.
erythromycin lactobionate.
erythromycin stearate.
idelalisib.
Cimetidine and quinidine. Taking either of these drugs with imipramine can lead to seizures, coma, and even death.
Propafenone and flecainide. ...
Selective serotonin reuptake inhibitors (SSRIs), such as sertraline, fluoxetine, and paroxetine.
Do not chew, crush or break it. Depsolam 0.25 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Depsolam 0.25 mg/25 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Depsolam 0.25 mg/25 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Depsolam 0.25 mg/25 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressant.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Depsolam 0.25 mg/25 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Depsolam 0.25 mg/25 mg Tablet may affect the levels of sugar in your blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depsolam 0.25 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
