Manufacturer: Zydus Cadila
Salt Composition : Budesonide(1mg)
Your doctor will tell you how often you need to use Derinide 1mg Respules. It is important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you do not have any symptoms. No symptoms mean that the medicine is doing its job. If you stop taking it your asthma may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler "reliever". To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it will not work as well.
The most common side effects are irritation in the throat, difficulty swallowing, and fungal infections in the mouth or throat. If you get these, do not stop taking it but do talk to your doctor. You can help prevent these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other rare, side effects that can be serious. Talk to your doctor if you are worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.
Before taking Derinide 1mg Respules, you should tell your doctor if you have tuberculosis, any infections in your mouth or lungs, or liver disease. While taking it you may be more at risk of getting infections so stay away from people with colds and flu. If you use Derinide 1mg Respules for a long time it may cause weak bones (osteoporosis) and damage to your eyes (glaucoma or cataracts). You might need tests for bone density and eye pressure. Ask your doctor whether it’s safe to take this medicine if you are pregnant or breastfeeding.
Budesonide is a potent topical anti-inflammatory agent. [19] It binds and activates glucocorticoid receptors (GR) in the effector cell (e.g., bronchial) cytoplasm that allows the translocation of this budesonide-GR complex in the bronchi nucleus, which binds to both HDCA2 and CBP (HAT).
Budesonide is a locally-acting glucocorticosteroid with an extensive, primarily hepatic, metabolism after oral administration. It is rapidly absorbed and biotransformed by cytochrome P450 (CYP) 3A to metabolites with negligible glucocorticoid activity
Difficulty in swallowing
Fungal infection of mouth
Fungal infection of oropharynx
Headache
Abdominal pain
Depression
Joint pain
Cushing syndrome
Dyspepsia
Increased risk of infection
Muscle pain
Muscle weakness
Muscle twitching
Osteoporosis
Irritability
Euphoria (feeling of intense excitement and happiness)
Budesonide is contraindicated in any patients with a history of hypersensitivity to budesonide or any of the ingredients of the budesonide formulation. The orally inhaled powder formulation of budesonide is contraindicated in patients with severe milk protein allergies
Derinide 1mg Respules may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Derinide 1mg Respules. Please consult your doctor.
Derinide 1mg Respules is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Budesonide extended release capsules are indicated for the treatment and maintenance of mild to moderate Crohn's disease. Various inhaled budesonide products are indicated for prophylactic therapy in asthma
Some products that may interact with this drug are: aldesleukin, mifepristone, drugs that can cause bleeding/bruising
Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Store below 30°C
If you miss a dose of Derinide 1mg Respules, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Derinide 1mg Respules ‘dampens down’ inflammation in the lungs to provide long-term (maintenance) treatment of asthma and prevent disease progression.
Derinide 1mg Respules will not work for an ongoing asthma attack. Use your rescue inhaler to control sudden difficulty in breathing.
Take it at the same time every day to prevent asthma attacks.
Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
Never breathe out into the mouthpiece.
Only minuscule amounts of Derinide 1mg Respules may get absorbed into the bloodstream after inhalation. Hence, serious side effects such or weight gain are unlikely.
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Q. Does Derinide 1mg Respules help with cough?
Derinide 1mg Respules helps relieve cough if it is caused due to asthma. In children, it is used to relieve cough which sounds like ‘dog bark’. This cough is caused due to irritation and swelling of the airways which further makes the airways narrow. As a result, when your child tries to breathe through the narrow passage, it becomes hard to breathe and causes coughing. Derinide 1mg Respules helps to reduce this irritation and swelling of the airways.
Q. Is Derinide 1mg Respules safe?
Derinide 1mg Respules is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. Does Derinide 1mg Respules raise blood sugar?
Yes, if you are taking Derinide 1mg Respules orally, your blood sugar levels may increase. However, with Derinide 1mg Respules inhalers, an increase in the blood sugar levels is very rare but may increase only if very high doses are taken for a very long time.
Q. Does Derinide 1mg Respules cause bone loss?
Derinide 1mg Respules being a steroid tends to decrease bone density, but this is usually seen in patients who take Derinide 1mg Respules in high doses and for a very long time. Take Derinide 1mg Respules as per the doctor’s advice to decrease the chances of developing decreased bone density.
