Derinide AQ 64mcg Nasal Spray

Manufacturer: Zydus Cadila

Salt Composition : Budesonide(64mcg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

You should always use Derinide-AQ Nasal Spray as advised by your doctor but to get the full benefit you should take it regularly. It may take a few days for the spray to take full effect. If you do not see an improvement in your symptoms after a week you should talk to your doctor.


The most common side effects of Derinide-AQ Nasal Spray include nasal irritation, nosebleeds, and throat irritation. Talk to your doctor if you are worried about side effects or they do not go away. Using corticosteroids like may Derinide-AQ Nasal Spray makes you more susceptible to viral infections, so you should stay away from people who have these infections. In general, try to avoid situations that make your symptoms worse (things like pollen and dust mites) and it is best not to smoke.


Before starting to use Derinide-AQ Nasal Spray you should let your doctor know if you are pregnant or breastfeeding, discuss the risks and benefits with your healthcare team.



Basic Information

Mechanism Of Action

Budesonide is a potent topical anti-inflammatory agent. [19] It binds and activates glucocorticoid receptors (GR) in the effector cell (e.g., bronchial) cytoplasm that allows the translocation of this budesonide-GR complex in the bronchi nucleus, which binds to both HDCA2 and CBP (HAT).

Pharmacokinets

Budesonide is a locally-acting glucocorticosteroid with an extensive, primarily hepatic, metabolism after oral administration. It is rapidly absorbed and biotransformed by cytochrome P450 (CYP) 3A to metabolites with negligible glucocorticoid activity

Side Effects

Nasal irritation

Nosebleeds

Headache

Abdominal pain

Depression

Joint pain

Cushing syndrome

Dyspepsia

Increased risk of infection

Muscle pain

Muscle weakness

Muscle twitching

Osteoporosis

Irritability

Euphoria (feeling of intense excitement and happiness)


Contra Indications

Budesonide is contraindicated in any patients with a history of hypersensitivity to budesonide or any of the ingredients of the budesonide formulation. The orally inhaled powder formulation of budesonide is contraindicated in patients with severe milk protein allergies

Pregnancy Related Information

Derinide-AQ Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

No interaction found/established


Breast Feeding Related Information

Derinide-AQ Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Budesonide extended release capsules are indicated for the treatment and maintenance of mild to moderate Crohn's disease. Various inhaled budesonide products are indicated for prophylactic therapy in asthma

Interactions

Some products that may interact with this drug are: aldesleukin, mifepristone, drugs that can cause bleeding/bruising 

Typical Dosage

Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

The right way to use the nasal spray:

Shake the bottle before using the medicine.

Clean your nose thoroughly before using the medicine.

Insert the bottle tip into one nostril and close the other nostril.

Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.

Breathe out gently through your mouth and repeat the same process for the other nostril.

Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.

Do not share the bottle with anyone else so that you do not spread germs.

Derinide-AQ Nasal Spray should be avoided in patients with recent nasal ulcers, nasal surgery, or nasal trauma.


How To Use

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.


FAQs

Q. Is Derinide-AQ Nasal Spray effective?

Derinide-AQ Nasal Spray is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Derinide-AQ Nasal Spray too early, the symptoms may return or worsen.

Q. How does Derinide-AQ Nasal Spray work?

Derinide-AQ Nasal Spray works by decreasing the inflammation caused by allergies. It reduces inflammation by blocking the release of certain natural substances that cause allergic symptoms such as swelling, redness and pain.

Q. For how long should I take Derinide-AQ Nasal Spray?

It is recommended that you take Derinide-AQ Nasal Spray for the duration advised by the doctor. Consult your doctor if you have any concerns.

Q. What is thrush? Can Derinide-AQ Nasal Spray cause thrush?

Thrush is a fungal infection of the nose and throat caused by candida. Derinide-AQ Nasal Spray can cause thrush as a common side effect. To avoid getting fungal infections, you should thoroughly rinse your mouth after using a nasal spray. If you experience any redness or white colored patches in your nose or mouth, inform your doctor.