Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Levosalbutamol(1.25mg), Budesonide(0.5mg)
Strip of 7 Respules
(Inclusive of all taxes)
Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your symptoms may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.
Levosalbutamol relaxes the smooth muscles of all airways, from the trachea to the terminal bronchioles. Increased cyclic AMP concentrations are also associated with the inhibition of the release of mediators from mast cells in the airways.
Budesonide is a potent topical anti-inflammatory agent. [19] It binds and activates glucocorticoid receptors (GR) in the effector cell (e.g., bronchial) cytoplasm that allows the translocation of this budesonide-GR complex in the bronchi nucleus, which binds to both HDCA2 and CBP
Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and undergoes extensive first-pass metabolism in the liver. Its oral bioavailability is stated to be only about 20%. It is widely distributed to body tissues and is highly bound to plasma proteins.
Levosalbutamol elicits an equal or slightly larger response than an equivalent dose of the racemic mixture. This is probably due to competitive inhibition between the enantiomers at beta-adrenoceptors. Pharmacokinetic-pharmacodynamic relationships for levosalbutamol show relatively large interindividual variations
Hoarseness of voice
Sore throat
Fungal infection of mouth
Respiratory tract infection
Headache
Muscle cramp
Contraindications. Bromhexine is contraindicated for use in patients with known hypersensitivity or idiosyncratic reaction to bromhexine hydrochloride
If you are allergic to levosalbutamol or similar medicines.
If you are on medications to treat your high blood pressure.
If you have a history of vaginal bleeding or bloody discharge during the first 6 months of pregnancy.
Derisal 0.5mg Respules 2ml may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Derisal 0.5mg Respules 2ml may cause excessive drowsiness with alcohol.
Derisal 0.5mg Respules 2ml is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
LEVOSALBUTAMOL+BUDESONIDE drugs Levosalbutamol and Budesonide that is used to prevent or treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD) such as shortness of breath, coughing or wheezing (whistling sound while breathing).
The risk or severity of hypokalemia can be increased when Budesonide is combined with Levosalbutamol. The risk or severity of hypertension can be increased when Levosalbutamol is combined with Bumadizone. The risk or severity of hypokalemia can be increased when Levosalbutamol is combined with Bumetanide
Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Store below 30°C
If you miss a dose of Derisal 0.5mg Respules 2ml, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Derisal 0.5mg Respules 2ml is a combination of two medicines that makes breathing easier for patients with asthma and chronic obstructive pulmonary disease (COPD).
This medicine is for inhalation only. The tablet should not be swallowed.
It should be taken at the same time each day.
It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Derisal 0.5mg Respules 2ml can lower blood potassium level.
Only miniscule amounts of Derisal 0.5mg Respules 2ml may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
