Deritas 7.5 Tablet PR (10'S)

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Darifenacin(7.5mg)


Deritas 7.5 Tablet PR is advised to take it in a dose and duration as per prescription. It can be taken with or without food. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.



Basic Information

Mechanism Of Action

Darifenacin works by blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. It thereby decreases the urgency to urinate

Pharmacokinets

From intravenous administration, it has been established that darifenacin possesses a moderate-to-high hepatic extraction ratio, with high plasma clearance (36-52 L/h) and a volume of distribution (165-276L) that exceeds total body water. It is highly protein bound (98%), primarily to alpha(1)-acid glycoprotein

Side Effects

Constipation

Dryness in mouth

Headache

Dry eye

Nasal dryness

Contra Indications

myasthenia gravis, a skeletal muscle disorder.

closed angle glaucoma.

ulcerative colitis, an inflammatory condition of the intestines.

blockage of the stomach or intestine.

liver problems.

severe liver disease.

blockage of the urinary bladder.

an inability to completely empty the bladder

Pregnancy Related Information

Deritas 7.5 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Deritas 7.5 Tablet PR. Please consult your doctor.


Breast Feeding Related Information

Deritas 7.5 Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Overactive Bladder. Indicated for overactive bladder with symptoms of urge incontinence, urgency, and frequency. Initial: 7.5 mg PO qDay. ...

Hepatic Impairment. Moderate: Do not exceed initial dose of 7.5 mg/day. Severe: Not recommended.

Administration. Swallow with water, do not crush, chew or cut.

Interactions

Acetophenazine Acetophenazine may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.

Aclidinium The risk or severity of adverse effects can be increased when Darifenacin is combined with Aclidinium.

Typical Dosage

 Deritas 7.5 Tablet PR may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Deritas 7.5 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Deritas 7.5 Tablet PR helps you to have better control over your urination by relaxing your bladder which increases its capacity to hold urine, thereby reducing the need to pass urine.

It may cause blurred vision, fatigue and sleepiness. Be cautious while driving or doing anything that requires focus.

It may cause dry mouth. Try chewing on sugar-free gum or taking small sips of water.

Avoid caffeine, alcohol or carbonated drinks as they can worsen your symptoms.

Do not stop taking this medicine if you do not notice an improvement in your symptoms as it may take some time for your bladder to adapt and your symptoms to improve.


How To Use

Use it as advised by your doctor or check the label for directions before use. Deritas 7.5 Tablet PR may be taken with or without food, but it is better to take it at a fixed time.