Manufacturer: Zuventus Healthcare Ltd
Salt Composition : Beclometasone, Neomycin, Clotrimazole
Dermitrust Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
Clotrimazole exerts its action primarily by damaging the permeability barrier in the fungal cytoplasmic membrane. Clotrimazole thereby inhibits the biosynthesis of ergosterol in a concentration-dependent manner by inhibiting the demethylation of 14 alpha lanosterol
Beclomethasone dipropionate works by attenuating the inflammatory responses associated with asthma, allergic rhinitis, nasal polyps, and corticosteroid-responsive dermatoses. It suppresses the actions of inflammatory cells, such as mast cells, eosinophils, basophils, lymphocytes, macrophages, and neutrophils
Neomycin is bactericidal in action. Similar to other aminoglycosides, it inhibits bacterial protein synthesis through irreversible binding to the 30 S ribosomal subunit of susceptible bacteria
After vaginal treatment with clotrimazole, the small fraction absorbed into the systemic circulation--between 3% and 10% of the dose--is subjected to metabolism and excretion as after oral or intravenous administration. The vaginal availability of clotrimazole is largely dependent on the formulation applied
Rapidly absorbed from pulmonary, nasal, and GI tissue. Undergoes extensive first-pass metabolism in the liver. Protein binding: 87%. Primarily eliminated in feces.
There is limited information on the metabolism of neomycin, as there is limited systemic absorption following drug administration. Metabolism is deemed to be negligible. The small absorbed fraction of neomycin is excreted by the kidney. The unabsorbed portion of the drug is excreted unchanged in the feces.
Application site reactions (burning, irritation, itching and redness)
Onychomycosis. Topical clotrimazole is not effective for onychomycosis. ...
Pregnancy. ...
Breast-feeding. ...
Contraceptive Devices, Menstruation. ...
Azole Antifungals Hypersensitivity. ...
Ocular Exposure, Ophthalmic Administration. .
active tuberculosis.
inactive tuberculosis.
herpes simplex infection of the eye.
a nasal fungal infection due to Candida.
an infection due to a parasite.
decreased function of the adrenal gland.
increased pressure in the eye.
wide-angle glaucoma.
Oral neomycin is contraindicated in intestinal obstruction and patients with a prior history of hypersensitivity. Patients with a history of hypersensitivity and serious toxic reactions to other aminoglycosides may have cross-sensitivity to neomycin.
Dermitrust Cream is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
No interaction found/established
Information regarding the use of Dermitrust Cream during breastfeeding is not available. Please consult your doctor.
Topical clotrimazole is used to treat tinea corporis (ringworm; fungal skin infection that causes a red scaly rash on different parts of the body), tinea cruris (jock itch; fungal infection of the skin in the groin or buttocks), and tinea pedis (athlete's foot; fungal infection of the skin on the feet
Beclomethasone is used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma in adults and children 5 years of age and older. It belongs to a class of medications called corticosteroids. It works by decreasing swelling and irritation in the airways to allow for easier breathing
include treatment for superficial eye infections, otitis externa, bacterial infections in skin, continuous short-term irrigant or rinse to prevent bacteriuria and gram-negative rod bacteremia in abacteriuric patients with indwelling catheters
Clotrimazole topical has no listed severe interactions with any other drugs.
Clotrimazole topical has no listed serious interactions with any other drugs.
Clotrimazole topical has no listed moderate interactions with any other drugs.
Clotrimazole topical has no listed minor interactions with any other drugs.
hepatic impairment.
hyperadrenocorticism.
infections.
ocular herpes simplex.
ocular toxicities.
osteoporosis.
dehydration.
neuromuscular blockade.
ototoxicity.
renal dysfunction.
intestinal obstruction.
colitis.
GI inflammation.
Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Dermitrust Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Dermitrust Cream helps treat skin infections.
It is for use on skin only. Do not use it in your eyes, mouth, or vagina. Rinse with cold water if you accidentally get it in these areas.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
If you think the area of skin you are treating has become more irritated, you should stop using Dermitrust Cream and consult your doctor.
Don't use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not improve after 1 week of treatment.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Q. How long does Dermitrust Cream takes to work?
Usually, Dermitrust Cream starts working soon after applying it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. Is it safe to use Dermitrust Cream?
Yes, Dermitrust Cream is safe when used according to your doctor’s advice and for limited duration of time. However, in some patients it may cause some unwanted side effects like transient burning, itching and irritation at the application site. It may also cause other uncommon or rare side effects. If you experience any persistent problem due to the medication, inform your doctor as soon as possible.
Q. Can I stop taking Dermitrust Cream when my symptoms are relieved?
No, do not stop taking Dermitrust Cream and complete the full course of treatment, even if you feel better. Your symptoms may improve before the skin infection is completely cured.
Q. What are the precautions needed to be taken while using Dermitrust Cream?
Dermitrust Cream should not be used on the face. Do not use the medication for longer than the advised periods of time. Do not apply a bandage or dressing to the area being treated, as this will increase the absorption of the preparation and increase the risk of side effects. This medicine should only be used by the patient and never be given to other people even if their condition appears to be the same.
Q. How to use Dermitrust Cream?
Follow the directions given by the healthcare provider on the medication. Apply the medication thinly and in sufficient quantity to cover the affected area completely. Dermitrust Cream is usually applied two or three times a day on the affected areas of skin. Wash your hands after using Dermitrust Cream, unless it is used for treating skin infection on the hands.
Q. Can I overuse Dermitrust Cream?
No, do not overuse Dermitrust Cream for long periods or on large areas of skin. It can cause over-absorption of the medicine into the body which may further lead to thinning or weakening of the skin and other serious side effects. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What is the storage condition for the Dermitrust Cream?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I stop using Dermitrust Cream when I feel better?
No, do not stop using Dermitrust Cream and finish the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cleared.
