Diachek 5mg Tablet (10'S)

Manufacturer: Cipla Ltd

Salt Composition : Glibenclamide(5mg)


Diachek 5mg Tablet may be used by itself or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.


Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.


The most common side effects of taking this medicine include nausea, headache, and dizziness. It can also sometimes cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Some people may find that they put on weight with this medicine.


You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.


Basic Information

Mechanism Of Action

Diachek 5mg Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Pharmacokinets

Background: Glibenclamide (Gb) may provoke long-lasting hypoglycaemic reactions, and one of the known risk factors is impaired renal function. We have demonstrated Gb to have a terminal elimination half-life of 15 h, and the main metabolites have a hypoglycaemic effect.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diachek

Hypoglycemia (low blood glucose level)

Nausea

Headache

Dizziness

Contra Indications

low blood sugar.

pituitary hormone deficiency.

a condition where the adrenal glands produce less hormones called Addison's disease.

glucose-6-phosphate dehydrogenase (G6PD) deficiency.

hepatic porphyria.

a type of blood disorder where the red blood cells burst called hemolytic anemia.

alcoholism.

Pregnancy Related Information

Diachek 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Diachek 5mg Tablet.


Breast Feeding Related Information

Diachek 5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Monitor the breastfed baby’s blood sugar during treatment with Diachek 5mg Tablet

Indications

Glibenclamide is an oral hypoglycemic (glucose lowering) drug used to control blood sugar levels in patients with type 2 diabetes in addition to diet and exercise. It belongs to the chemical group of sulfonylureas.

Interactions

Glibenclamide can interact with the following medications when taken together: Drugs like non-steroidal painkillers, ciprofloxacin and propranolol can increase the chances of lowering the blood sugar levels below normal and resulting in hypoglycemia. Bosentan can increase the risk of liver damage.

Typical Dosage

 Do not chew, crush or break it. Diachek 5mg Tablet is to be taken with food.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

You should skip a dose of Diachek 5mg Tablet if a meal is skipped, and add a dose of medicine if you eat an extra meal.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.

Be careful while driving or operating machinery until you know how Diachek 5mg Tablet affects you.

It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.

Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diachek 5mg Tablet is to be taken with food.


FAQs

Q. Is Diachek 5mg Tablet the same as Glipizide?

No, Diachek 5mg Tablet and Glipizide are different medicines. However, they belong to the same class of medicines called sulfonylureas and are used to treat type 2 diabetes mellitus in adults.

Q. Does Diachek 5mg Tablet play any role in the treatment of polycystic ovarian syndrome (PCOS)?

No, Diachek 5mg Tablet is not known to have any role in the treatment of polycystic ovarian syndrome (PCOS). Also, there is no clinical evidence available regarding the same.

Q. Why should Diachek 5mg Tablet be used cautiously in elderly patients?

Diachek 5mg Tablet should be used with extra caution in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event).

Q. Is Diachek 5mg Tablet useful in the management of prediabetes?

Diachek 5mg Tablet is not used for the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. There are clinical studies available, but the evidence is not strong enough for its use in prediabetes.