Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Diclofenac(50mg), Paracetamol(325mg), Serratiopeptidase(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Diclomore SP Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
As with all NSAIDs, diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.
Anti-inflammatory: Serratiopeptidase acts as an anti-inflammatory agent by regulating inflammatory cytokines and hence the onset of chronic inflammation. It significantly modifies cell adhesion molecules that guide inflammatory cells to the sites of inflammation.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors.
Diclofenac binds extensively to plasma albumin. The area under the plasma concentration-time curve (AUC) of diclofenac is proportional to the dose for oral doses between 25 to 150 mg. Substantial concentrations of drug are attained in synovial fluid, which is the proposed site of action for NSAIDs.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Serratiopeptidase reduces pain and swelling without inhibiting prostaglandins and has no gastrointestinal adverse effects. It also acts by enhancing blood circulation due to proteolytic effect, removing damaged and denatured proteins and cellular debris, and modulating inflammatory cytokines.
Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
ischaemic heart disease.
peripheral arterial disease.
cerebrovascular disease.
congestive heart failure
Serrapeptase should not be taken along with blood thinners — such as Warfarin and aspirin — other dietary supplements like garlic, fish oil, and turmeric, which may increase your risk of bleeding or bruising. Several side effects have been observed in people taking serrapeptase.
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
Diclomore SP Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Diclomore SP Tablet.
Information regarding the use of Diclomore SP Tablet during breastfeeding is not available. Please consult your doctor.
Diclofenac is indicated for treatment of primary dysmenorrhea, for relief of mild to moderate pain, for relief of the signs and symptoms of osteoarthritis, for relief of the signs and symptoms of rheumatoid arthritis, for relief of symptoms of ankylosing spondylitis and for relief of acute migraine symptoms
Serratiopeptidase is often used in oral surgery for its anti-inflammatory purpose after impaction surgery, maxillofacial trauma and infections but its use should be limited in cases of abscess due to its fibrinolytic activity.
Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea
apixaban.
benazepril.
captopril.
enalapril.
fosinopril.
ketorolac.
ketorolac intranasal.
lisinopril.
skin reactions.
muscle and joint pain.
poor appetite.
nausea.
stomach pain.
cough.
blood clotting disturbances
Arguably, the most important pharmacodynamic drug interaction with paracetamol is that of N-acetylcysteine in attenuating the hepatotoxicity that results from supratherapeutic intake and overdose of paracetamol. The role of N-acetylcysteine in managing paracetamol overdose is well established.
Do not chew, crush or break it. Diclomore SP Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Diclomore SP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Diclomore SP Tablet affects you.
Avoid consuming alcohol when taking Diclomore SP Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diclomore SP Tablet is to be taken with food.
Q. What are the storage condition for Diclomore SP Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is Diclomore SP Tablet?
Diclomore SP Tablet is a combination of three medicines: Diclofenac, Paracetamol, and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that causes pain and inflammation.
Q. Is it safe to use Diclomore SP Tablet?
Yes, Diclomore SP Tablet is safe for most of the patients, however, in some patients it may cause common unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Q. Can I stop taking Diclomore SP Tablet when my pain is relieved?
Diclomore SP Tablet is usually used for a short term and can be discontinued when the pain is relieved. However, Diclomore SP Tablet should be continued if you are advised by your physician to do so.
Q. Can the use of Diclomore SP Tablet cause nausea and vomiting?
Yes, the use of Diclomore SP Tablet can cause nausea and vomiting.Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. Can the use of Diclomore SP Tablet cause dizziness?
Yes, the use of $ame can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines.
Q. Are there any specific contraindications associated with the use of Diclomore SP Tablet?
The use of Diclomore SP Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Q. Can I take Diclomore SP Tablet with Vitamin B-complex?
Diclomore SP Tablet can be taken with Vitamin B-complex preparations. While Diclomore SP Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.
Q. Can I take Diclomore SP Tablet for stomach pain?
No, Diclomore SP Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Q. Can the use of Diclomore SP Tablet cause damage to kidneys?
No, taking higher than the recommended dose of Diclomore SP Tablet can lead to increased chances of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
