Manufacturer: Nitin Lifesciences Ltd
Salt Composition : Glimepiride(1mg), Metformin(500mg), Pioglitazone(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dikort G 1mg/500mg/15mg Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.
Dikort G 1Mg/500Mg/15Mg Tablet is a salt which performs its action by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Dikort G 1Mg/500Mg/15Mg Tablet is used to treat conditions such as Type II Diabetes Mellitus.
Glimepiride is completely metabolized by oxidative biotransformation after either an IV or oral dose. The major metabolites are the cyclohexyl hydroxy methyl derivative (M1) and the carboxyl derivative (M2). Cytochrome P450 2C9 has been shown to be involved in the biotransformation of glimepiride to M1.Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.Pioglitazone is a thiazolidinedione that increases insulin sensitivity in target tissues. It is well-absorbed, with a mean absolute bioavailability of 83% and reaching maximum concentrations in around 1.5 hours. It is metabolised by the hepatic cytochrome P450 enzyme system.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dikort G
Hypoglycemia (low blood glucose level)
Dizziness
Headache
Nausea
Vomiting
Diarrhea
Flatulence
Bronchitis (inflammation of the airways)
Anemia (low number of red blood cells)
Edema (swelling)
Hypersensitivity to Dikort G Tablet is a contraindication. In addition, Dikort G Tablet should not be used if you have the following conditions:
Acute myocardial infarction
Cardiovascular collapse
Diabetic ketoacidosis
Hypersensitivity
Hypersensitivity to sulfonamide derivatives
Hypersensitivity to this drug
Renal disease
Septicemia
Type 1 diabetes mellitus
Dikort G 1mg/500mg/15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Dikort G 1mg/500mg/15mg Tablet.
Dikort G 1mg/500mg/15mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
The combination of modern sulfonylurea (glimepiride) and metformin is widely prescribed for effective blood glucose control due to its capability of counteracting “insulin secretion disorder” and “insulin resistance,” respectively.
If you use other drugs or over the counter products at the same time, the effects of Dikort G Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Dikort G Tablet may interact with the following drugs and products:
Albuterol
Alcohol
Anabolic steroids
Androgens
Angiotensin converting enzyme inhibitors
Anti-diabetic drugs
Atypical antipsychotic medications
Barbiturates
Beta blockers
Chloramphenicol
Do not chew, crush or break it. Dikort G 1mg/500mg/15mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Dikort G 1mg/500mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dikort G 1mg/500mg/15mg Tablet is to be taken with food.
Q. Can I drink alcohol while taking Dikort G 1mg/500mg/15mg Tablet?
No, it is not safe to drink alcohol while using Dikort G 1mg/500mg/15mg Tablet. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.
Q. What should I inform the doctor before taking Dikort G 1mg/500mg/15mg Tablet?
Before taking Dikort G 1mg/500mg/15mg Tablet inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.
Q. Can the use of Dikort G 1mg/500mg/15mg Tablet lead to Vitamin B12 deficiency?
Yes, the use of Dikort G 1mg/500mg/15mg Tablet can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.
Q. Can the use of Dikort G 1mg/500mg/15mg Tablet cause hypoglycemia?
Yes, the use of Dikort G 1mg/500mg/15mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.
Q. What are the instructions for the storage and disposal of Dikort G 1mg/500mg/15mg Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
