Manufacturer: Pfizer Ltd
Salt Composition : Phenytoin(50mg/2ml)
Vial of 2ml Injection
(Inclusive of all taxes)
Dilantin 50mg/2ml Injection is given under the supervision of a healthcare professional and should not be self-administered. It is advisable to take it at the same time each day as this helps to maintain a constant level of medicine in the body. If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better as stopping the medication without talking to your doctor may cause non-stop seizures (called status epilepticus), which can be life-threatening.
Dilantin 50mg/2ml Injection is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence.
Phenytoin follows nonlinear (or zero-order) kinetics at therapeutic concentrations, because the rate of metabolism is close to the maximum capacity of the enzymes involved. In nonlinear kinetics, clearance and half-life fluctuate with plasma concentration.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dilantin
Rash
Headache
Dizziness
Vomiting
Nausea
Slurred speech
Vertigo
Confusion
Nervousness
Constipation
Tremors
Altered walking
diabetes
osteomalacia, or softening of bones
porphyria
megaloblastic anemia
a type of blood disorder with a decrease in all types of blood cells called pancytopenia
decreased blood platelets
very low levels of granulocytes, a type of white blood cell
low levels of white blood cells
low levels of granulocytes, a type of white blood cell
suicidal thoughts
alcoholism
alcohol intoxication
depression
myasthenia gravis, a skeletal muscle disorder
hardening of the arteries due to plaque buildup
overgrowth of gums onto teeth
liver problems
decreased kidney function
systemic lupus erythematosus, an autoimmune disease
osteoporosis, a condition of weak bones
decreased calcification or density of bone
a body temperature higher than 101 degrees Fahrenheit
swollen lymph nodes
pregnancy
CYP2C9 poor metabolizer
HLA-B *15:02 positive gene status
Dilantin 50mg/2ml Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Dilantin 50mg/2ml Injection.
Dilantin 50mg/2ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Phenytoin is indicated to treat grand mal seizures, complex partial seizures, and to prevent and treat seizures during or following neurosurgery.
If you use other drugs or over the counter products at the same time, the effects of Dilantin Capsule may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Dilantin Capsule may interact with the following drugs and products:
Carbamazepine
Clonazepam
Cyclosporine
Digoxin
Disopyramide
Doxycycline
Estrogens
Oral contraceptives
Paroxetine
Phenobarbital
Kindly do not self administer.
Store below 30°C
If you miss a dose of Dilantin 50mg/2ml Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
It may increase blood sugar levels. Inform your doctor if you are taking any medicines to treat diabetes.
It may cause swollen gum (gum hypertrophy), hence take care of oral or dental hygiene.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. For how long does Dilantin 50mg/2ml Injection stay in your system?
On an average, Dilantin 50mg/2ml Injection may stay in your system for 5-6 days. This duration varies from person to person. In some cases, it may stay for about 9-10 days.
Q. Who should avoid taking Dilantin 50mg/2ml Injection?
You should not take Dilantin 50mg/2ml Injection if you have liver disease, especially if you have a history of developing a liver problem due to Dilantin 50mg/2ml Injection. Also, patients taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Dilantin 50mg/2ml Injection. Dilantin 50mg/2ml Injection may reduce the effectiveness of Delavirdine on HIV and the virus may also become resistant to Delavirdine. It is advised that you inform your doctor if you have any existing heart disorder before you receive Dilantin 50mg/2ml Injection.
Q. Can I take Dilantin 50mg/2ml Injection with ibuprofen?
Dilantin 50mg/2ml Injection can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. What are the effects of Dilantin 50mg/2ml Injection on children?
The most common side effects related to Dilantin 50mg/2ml Injection in children are jerky movements of the eyes (nystagmus) and overgrowth of the gums. In some children, Dilantin 50mg/2ml Injection causes problems with thinking or behavior, mood change, slow or clumsy movements, or a loss of energy. Other side effects from high doses include unsteadiness in the feet and hands, sleepiness, and vomiting. These may be avoidable if the dose is increased slowly. These side effects quickly disappear when the dose is reduced.
Q. Does Dilantin 50mg/2ml Injection cause weight gain?
Dilantin 50mg/2ml Injection has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Dilantin 50mg/2ml Injection. Please consult your doctor if you experience weight gain after taking Dilantin 50mg/2ml Injection.
Q. Does Dilantin 50mg/2ml Injection make you sleepy?
Dilantin 50mg/2ml Injection can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Dilantin 50mg/2ml Injection, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.
Q. Does Dilantin 50mg/2ml Injection affect birth control?
Dilantin 50mg/2ml Injection does affect birth control. Dilantin 50mg/2ml Injection can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.
