Manufacturer: Divine Lifecare Pvt Ltd
Salt Composition : Ofloxacin(200mg), Tinidazole(600mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dioflox TZ 200 mg/600 mg Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.
Ofloxacin is a quinolone antimicrobial agent. The mechanism of action of ofloxacin and other fluoroquinolone antimicrobials involves inhibition of bacterial topoisomerase IV and DNA gyrase (both of which are type II topoisomerases), enzymes required for DNA replication, transcription, repair and recombination
Tinidazole is an antiprotozoal, antibacterial agent. The nitro- group of tinidazole is reduced by cell extracts of Trichomonas. The free nitro- radical generated as a result of this reduction may be responsible for the antiprotozoal activity.
The pharmacokinetics of ofloxacin are characterised by almost complete bioavailability (95 to 100%), peak serum concentrations in the range of 2 to 3 mg/L after a 400mg oral dose and an average half-life of 5 to 8h
The plasma half-life of tinidazole is approximately 12-14 hours. Tinidazole is excreted by the liver and the kidneys. Tinidazole is excreted in the urine mainly as unchanged drug (approximately 20-25% of the administered dose). Approximately 12% of the drug is excreted in the feces
Nausea
Dryness in mouth
Metallic taste
Headache
diarrhea from an infection with Clostridium difficile bacteria.
diabetes.
low blood sugar.
dehydration.
low amount of potassium in the blood.
a low seizure threshold.
a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.
Contraindicated in patients with a prior history of hypersensitivity to tinidazole or other nitroimidazole derivatives and during the first trimester of pregnancy. Use with caution and reduce dose in severe hepatic Impairment
Dioflox TZ 200 mg/600 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Dioflox TZ 200 mg/600 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Dioflox TZ 200 mg/600 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Tablets are indicated for the treatment of adults with mild to moderate infections (unless otherwise indicated) caused by susceptible strains of the designated microorganisms in the infections listed below
Tinidazole is indicated for the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, or anaerobic vaginosis) in non-pregnant women
Some products that may interact with this drug include: alcohol-containing products (such as cough and cold syrups, aftershave), products containing propylene glycol, lopinavir/ritonavir solution, lithium. Do not take tinidazole if you are also taking disulfiram or if you have taken disulfiram within the last 2 weeks
blood thinners" (such as acenocoumarol, warfarin), strontium. Many drugs besides ofloxacin may affect the heart rhythm (QT prolongation), including dofetilide, procainamide, amiodarone, quinidine, sotalol, among others. Ofloxacin is very similar to levofloxacin.
Some products that may interact with this drug include: alcohol-containing products (such as cough and cold syrups, aftershave), products containing propylene glycol, lopinavir/ritonavir solution, lithium. Do not take tinidazole if you are also taking disulfiram or if you have taken disulfiram within the last 2 weeks
Do not chew, crush or break it. Dioflox TZ 200 mg/600 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Dioflox TZ 200 mg/600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you.
Consult your doctor if your diarrhea lasts for more than 48 hours.
Do not use Dioflox TZ 200 mg/600 mg Tablet if you have blood in your stool or if you are severely constipated.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Dioflox TZ 200 mg/600 mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dioflox TZ 200 mg/600 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can the use of Dioflox TZ 200 mg/600 mg Tablet cause dryness in the mouth?
Yes, the use of Dioflox TZ 200 mg/600 mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Q. Is it safe to take Dioflox TZ 200 mg/600 mg Tablet while breastfeeding?
Dioflox TZ 200 mg/600 mg Tablet should be used with caution in nursing mothers as it can lead to serious side effects. You should always consult your doctor before taking Dioflox TZ 200 mg/600 mg Tablet.
Q. Can the use of Dioflox TZ 200 mg/600 mg Tablet cause metallic taste?
Yes, the use of Dioflox TZ 200 mg/600 mg Tablet can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.
Q. Can I take a higher than the recommended dose of Dioflox TZ 200 mg/600 mg Tablet?
No, taking a higher than the recommended dose of Dioflox TZ 200 mg/600 mg Tablet can lead to increased side effects. If you are experiencing increased severity of your symptoms which are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. Are there any specific contraindications associated with the use of Dioflox TZ 200 mg/600 mg Tablet?
The use of Dioflox TZ 200 mg/600 mg Tablet is considered to be harmful for patients with known allergy to ofloxacin or tinidazole or any other excipient. It should preferably be avoided in patients with a history of any inflammation of the tendons (tendinitis), or tendon rupture seen with the use of ofloxacin or any other medicine which belongs to the same group (quinolone group) of antimicrobial agents and in patients with some neurological disorders.
Q. What are the instructions for the storage and disposal of Dioflox TZ 200 mg/600 mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What if I don't get better after using Dioflox TZ 200 mg/600 mg Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Dioflox TZ 200 mg/600 mg Tablet when I feel better?
No, do not stop taking Dioflox TZ 200 mg/600 mg Tablet and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.
Q. What if I miss my dose?
Take Dioflox TZ 200 mg/600 mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
Q. For how long should you take Dioflox TZ 200 mg/600 mg Tablet?
It is usually taken with or without food, twice a day, for 3 days to 6 weeks. The length of treatment depends on the type of infection being treated. Always consult the doctor before taking the medicine.
Q. Can a person drive while taking Dioflox TZ 200 mg/600 mg Tablet?
No, taking Dioflox TZ 200 mg/600 mg Tablet may make you feel sleepy, dizzy and may lead to visual disturbances. So, do not drive or use machines while you are on this medicine.
