Manufacturer: Unison Pharmaceuticals Pvt Ltd
Salt Composition : Caffeine(30mg), Chlorpheniramine Maleate(4mg), Paracetamol(500mg), Phenylephrine(10mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Diominic Dca Tablet is used in the treatment of nasal and sinus congestion, sinus pain, and headache. It is also used to provide relief of allergic symptoms of the nose/throat due to upper respiratory tract allergies. Take Diominic Dca Tablet in the exact dose and duration as prescribed by your doctor. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.
Diominic Dca Tablet contains a combination of paracetamol, phenylephrine, chlorpheniramine, and caffeine as active substances.Paracetamol is a non-steroidal anti-inflammatory medicine (NSAID) that blocks the action of a chemical called cyclooxygenase. Cyclooxygenase is responsible for the formation of certain substances in the body called prostaglandins that cause fever, pain and inflammation.Chlorpheniramine is an anti-allergic medicine that blocks certain proteins in the body that are responsible for causing itching of the nose/throat, watery eyes, runny nose and sneezing due to respiratory allergies.Phenylephrine produces constriction of the blood vessels of the nose which reduces the fluid accumulation and clears the nasal blockage.Caffeine increases the pain-relieving activity of paracetamol and reduces the incidence of drowsiness due to chlorpheniramine.
Caffeine is rapidly and completely absorbed within an hour following ingestion. It is distributed throughout body water and readily crosses cell membranes including the brain. Its primary mechanisms for stimulatory activity appear to be the blocking of adenosine receptors and inhibition of phosphodiesterases.Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration [1, 8]. It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diominic Dca
Restlessness
Increased heart rate
Increased production of urine
Dryness in mouth
Sleepiness
Drowsiness
Loss of appetite
Nausea
Vomiting
Insomnia (difficulty in sleeping)
Headache
Constipation
Itching
Vomiting
Headache
High blood pressure
Arrhythmia (irregular heartbeats)
Blurred vision
Breathlessness
Itching
Reflex bradycardia
Excitation
Epigastric pain
Neck pain
Tremors
Hypertensive crisis
Eye pain
Stinging in the eyes
Photophobia
Conjunctival sensitivity
Preterm and low birth weight infants
Fainting
Myocardial infarction
Subarachnoid hemorrhage
If you are suffering from any of the following diseases, you should not take Caffeine + Chlorpheniramine + Paracetamol + Phenylephrine unless your doctor advises you to do so -
High Blood Pressure
Heart Disease
Liver Disease
Diominic Dca Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Diominic Dca Tablet.
Diominic Dca Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Diominic Dca Tablet is a combination of four medicines: Caffeine , Chlorpheniramine Maleate , Paracetamol , and Phenylephrine, which relieves common cold symptoms. Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Caffeine increases the effectiveness of paracetamol and makes you more alert. Phenylephrine is a decongestant which narrows the small blood vessels providing temporary relief from congestion or stuffiness in the nose.
If you use other drugs or over the counter products at the same time, the effects of Diominic Dca Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Diominic Dca Tablet may interact with the following drugs and products:
Alcohol
Antipsychotics
Cimetidine
Decongestants
Digoxin
Disulfiram
Ephedrine
Fluoroquinolones
High blood pressure medicines
Interfere with certain laboratory tests
Do not chew, crush or break it. Diominic Dca Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Diominic Dca Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Caffeine
Caffeine helps in the treatment of interrupted breathing in premature babies.
It is given by mouth or via a gastric feeding tube by a doctor or nurse.
If you are breast-feeding while your infant is treated with Caffeine, do not drink coffee or take any other high caffeine product as caffeine passes into breast milk.
Chlorpheniramine Maleate
Avoid driving or operating dangerous machinery as it may decrease alertness.
Avoid consuming alcohol when taking the Chlorpheniramine Maleate, as it may cause excessive sleepiness or drowsiness.
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylephrine
Oral phenylephrine should be taken with food
Phenylephrine can make you restless, so don't take it too close to bedtime
Do not use this medicine without doctor's advice if you are pregnant or breast feeding
Smoking may worsen the effect; therefore use of tobacco should be avoided.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diominic Dca Tablet may be taken with or without food, but it is better to take it at a fixed time.
