Manufacturer: Orchid Chemicals & Pharmaceuticals Ltd
Salt Composition : Mifepristone(200mg), Misoprostol(200mcg)
Dismis MM Kit should be taken with food or as per your doctor's advice. You must start with a dose of Mifepristone. It should be taken orally, by swallowing the tablets whole with a glass of water. If you experience vomiting within 30 minutes of tablet intake, inform your doctor or take another tablet. The medicine may take 24- 48 hours to show its action and you might experience spotting or bleeding. After a period of 36-48 hours, you have to take Misoprostol tablet, either orally or vaginally. You are suggested to have proper rest after this dose intake as it may cause severe stomach pain or vaginal bleeding thus leading to abortion.
Dismis MM Kit is a combination of two medicines: Mifepristone and Misoprostol, which causes abortion. Mifepristone blocks the effects of progesterone, a natural female hormone that is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnancy. Misoprostol increases contractions of the uterus to cause abortion.
The pharmacokinetics of mifepristone are characterised by rapid absorption, a long half-life of 25 to 30 hours and micromolar serum concentrations following ingestion of doses currently in clinical use. The serum transport protein alpha 1-acid glycoprotein (AAG) regulates the serum kinetics of mifepristone.Early studies concentrated on the pharmacokinetic properties after oral administration. After oral administration, misoprostol is rapidly and almost completely absorbed from the gastrointestinal tract. However, the drug undergoes extensive and rapid first-pass metabolism (de-esterification) to form misoprostol acid.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dismis MM
Nausea
Vomiting
Diarrhea
Stomach cramp
Uterine contractions
Menorrhagia (heavy menstrual bleeding)
Hypersensitivity to Dismis Mm Kit is a contraindication. In addition, Dismis Mm Kit should not be used if you have the following conditions:
Cardiovascular disease
Cerebrovascular disease
Chronic adrenal failure
Elderly and renal impairment
Hemorrhagic disorder
Hypersensitivity
Inherited porphyrias
Pregnancy and lactation
Suspected ectopic pregnancy
Dismis MM Kit is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is unsafe to consume alcohol with Dismis MM Kit.
Dismis MM Kit is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
The Mifeprex brand of mifepristone is indicated for the medical termination of intrauterine pregnancy through 70 days gestation in combination with misoprostol.
If you use other drugs or over the counter products at the same time, the effects of Dismis Mm Kit may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Dismis Mm Kit may interact with the following drugs and products:
Amprenavir
Aspirin
Bepridil
Ceritinib
Cervidil
Corticotropin
Danaparoid
Dinoprostone topical
Ergometrine
Gemeprost
Do not chew, crush or break it. Dismis MM Kit is to be taken with food.
Store below 30°C
If you miss a dose of Dismis MM Kit, please consult your doctor.
Consult a doctor before taking any medicines.
Dismis MM Kit helps terminate a pregnancy.
Use caution while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
It does not affect fertility. Use contraception to avoid pregnancy.
For pregnancy termination:
Take it no later than 63 days after the first day of your last menstrual period.
Take Misoprostol 36 – 48 hours after taking Mifepristone.
Rest for at least 3 hours after taking the Misoprostol.
Take it only as prescribed by the doctor. Miscarriages, if incomplete, may result in serious medical complications leading to hospitalization, surgery and possible infertility.
Vaginal bleeding lasting for approximately 12 days may occur after taking this medicine. Inform your doctor immediately if excessive bleeding occurs or if you suffer from severe abdominal pain.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dismis MM Kit is to be taken with food.
Q. What is Dismis MM Kit and what is it used for?
Dismis MM Kit contains two medicines, Mifepristone, and Misoprostol. Dismis MM Kit is used for medical termination of pregnancy. It is only used to terminate a pregnancy which should not be more than 63 days old, counting from the first day of the last menstrual period.
Q. How and in what dose should I take Dismis MM Kit?
Dismis MM Kit should only be taken as per the advice of the doctor. The course is started with Mifepristone. Misoprostol is advised after 36-48 hours of taking Mifepristone. However, Misoprostol should only be taken under the supervision of a gynecologist, at a clinic or hospital setting.
Q. What should I expect after completing my course of Dismis MM Kit?
After taking Mifepristone, you may or may not experience vaginal bleeding. However, you may experience abdominal cramping, diarrhea, stomach pain, and nausea immediately after taking Misoprostol. You may also have vaginal bleeding within 4 hours of taking Misoprostol. You may also be asked to stay at the clinic or healthcare center for at least 3 hours after taking this medicine. After 14 days of taking Mifepristone (pill you took before Misoprostol), your gynecologist may run some blood tests or perform ultrasonography to confirm whether pregnancy has been terminated or not.
Q. Can Dismis MM Kit affect my future chances of getting pregnant?
No, studies have shown that this medicine does not impair the fertility of the women. Your future chances of getting pregnant are as equal as those who have not taken this medicine.
Q. What are the common side effects of taking Dismis MM Kit?
The common side effects of using Dismis MM Kit are abdominal pain, abdominal cramping, nausea, diarrhea, dizziness, uterine contractions, pelvic pain, and shivering. If you experience a very heavy vaginal bleeding or if any of these side effects bother you please consult with your gynecologist.
