Manufacturer: Strides shasun Ltd
Salt Composition : Domperidone(10mg), Paracetamol(325mg), Tramadol(37.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dismol DP 10 mg/325 mg/37.5 mg Tablet can be taken with or without food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.Using this medicine may cause few common side effects such as nausea, vomiting, constipation, and dry mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.
Dismol DP 10 mg/325 mg/37.5 mg Tablet is used to treat severe acute pain in conditions like menstrual cramp, arthritis, headache and muscle aches. It works by reducing substances in the body that causes pain. It also decreases tendency of nausea and vomiting associated with headache or menstrual cramps.
The absorption of domperidone was very rapid, with mean peak plasma concentration (Cmax) values of 18.8, 15.0, and 20.7 ng/mL attained at 0.9, 1.2, and 0.6 hours after the administration of base tablet, maleate tablet, and solution, respectively. The mean elimination half-life (t1/2) ranged from 12.6 to 16.0 hours.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.Tramadol is rapidly distributed in the body; plasma protein binding is about 20%. Tramadol is mainly metabolised by O- and N-demethylation and by conjugation reactions forming glucuronides and sulfates. Tramadol and its metabolites are mainly excreted via the kidneys. The mean elimination half-life is about 6 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dismol DP
Nausea
Vomiting
Constipation
Dryness in mouth
Sleepiness
Weakness
Dizziness
Dismol Dp Tablet has a contraindication for hypersensitivity . In addition, Dismol Dp Tablet should not be consumed if you have the following conditions :
Concomitant use of drugs that prolong the QT interval
domperidone hypersensitivity reaction
hypersensitive
Use of antidepressants
Patients with significant electrolyte disturbances
Presence of mechanical obstruction or perforation of the gastrointestinal tract
Presence due to gastrointestinal bleeding
Severe renal impairment
Impairment of the liver
Co-administration with potent CYP3A4 inhibitors
Dismol DP 10 mg/325 mg/37.5 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Dismol DP 10 mg/325 mg/37.5 mg Tablet.
Dismol DP 10 mg/325 mg/37.5 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Use with caution
Below 9years: Contraindicated
Domperidone+Paracetamol+Tramadol is used for pain relief and severe acute pain.Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking the transmission of pain signals to the brain to lower pain perception.
If you take other medicines or over the counter products at the same time, the effect of Dismol Dp Tablet may change. This can increase the risk of side effects or prevent the medicine from working. Tell your doctor about all the medications, vitamins, and herbal supplements you are using so your doctor can help prevent and manage drug reactions. Dismol Dp Tablet may interact with the following drugs and products:
Alcohol
Amiodarone
Amprenavir
Antacids
Aprepitant
Atazanavir
Atropine
Buprenorphine
Bupropion
Carbamazepine
Do not chew, crush or break it. Dismol DP 10 mg/325 mg/37.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Dismol DP 10 mg/325 mg/37.5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Dismol DP 10 mg/325 mg/37.5 mg Tablet in case of severe painful conditions as well as to prevent vomiting.
Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Seek medical attention right away if you have symptoms, such as: agitation, sweating, shivering, fast heart rate, muscle stiffness, twitching or loss of coordination.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dismol DP 10 mg/325 mg/37.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What are the instructions for the storage and disposal of Dismol DP 10 mg/325 mg/37.5 mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I discontinue the medicine when my pain is relieved?
Dismol DP 10 mg/325 mg/37.5 mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Dismol DP 10 mg/325 mg/37.5 mg Tablet should be continued if advised by the doctor.
Q. Can the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet cause constipation?
Yes, the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet can cause constipation. Talk to your doctor about treating constipation, if it persists for a long time.
Q. Are there any specific contraindications associated with the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet?
Dismol DP 10 mg/325 mg/37.5 mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. Dismol DP 10 mg/325 mg/37.5 mg Tablet can cause problems when used with the medicine that can cause sleepiness. It should also be avoided with MAO inhibitors (certain medicines that are used in the treatment of depression or Parkinson’s disease). Dismol DP 10 mg/325 mg/37.5 mg Tablet should not be used in patients who are suffering from severe liver disease or epilepsy.
Q. Can the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet cause damage to the liver?
Dismol DP 10 mg/325 mg/37.5 mg Tablet is usually safe when consumed in the recommended dose. However, an overdose of Dismol DP 10 mg/325 mg/37.5 mg Tablet can damage your liver. Avoid drinking alcohol while taking this medicine, it may increase your risk of liver damage.
Q. Can the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet cause dry mouth?
Yes, the use of Dismol DP 10 mg/325 mg/37.5 mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Q. Can I take a higher than the recommended dose of Dismol DP 10 mg/325 mg/37.5 mg Tablet?
No, taking a higher than the recommended dose of Dismol DP 10 mg/325 mg/37.5 mg Tablet can lead to increased chances of side effects and liver damage. If the recommended dosage does not relieve your symptoms or you experience increased severity of pain, please consult your doctor for re-evaluation.
