Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Divalproex(125mg)
Strip of 10 Tablet Er
(Inclusive of all taxes)
Divaa-OD 125 Tablet ER may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. You can take this medicine with or without food but take it at the same time each day to get the most benefit.
Divaa-OD 125 Tablet ER is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence.
Divalproex sodium dissociates to the valproate ion in the gastrointestinal tract. The mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of gamma-aminobutyric acid (GABA).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Divaa
Headache
Dizziness
Blurred vision
Weakness
Abdominal pain
Infection
Nausea
Vomiting
Sleepiness
Hair loss
Weight gain
Double vision
Diarrhea
Tremors
Weight loss
Flu-like symptoms
high amount of ammonium in the blood
low amount of albumin proteins in the blood
hereditary liver metabolism disorder
decreased blood platelets
suicidal thoughts
depression
organic mental disorder
liver problems
acute inflammation of the pancreas
pregnancy
citrullinemia
ornithine carbamoyltransferase deficiency
hereditary disease causing neurologic dysfunction
urea cycle disorder
Divaa-OD 125 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Divaa-OD 125 Tablet ER may cause excessive drowsiness with alcohol.
Divaa-OD 125 Tablet ER is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Divalproex is a valproate and is indicated for the treatment of the manic episodes associated with bipolar disorder. A manic episode is a distinct period of abnormally and persistently elevated, expansive, or irritable mood.
DIVALPROEX may interact with other anticonvulsants (phenobarbital, primidone, phenytoin, carbamazepine, ethosuximide, lamotrigine, topiramate, and felbamate), salicylate (aspirin), antidepressants (diazepam and amitryptiline), antiretroviral drug (zidovudine), antibiotics (rifampicin), and anticoagulant drug (warfarin).
Do not chew, crush or break it. Divaa-OD 125 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Divaa-OD 125 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
It can be taken with or without food, but better to take with food to avoid stoamch upset.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Your doctor may get regular blood tests done to monitor how the medication is affecting your body. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Divaa-OD 125 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Q. What happens if I stop taking Divaa-OD 125 Tablet ER?
You should not stop taking Divaa-OD 125 Tablet ER without consulting your doctor. The dose of Divaa-OD 125 Tablet ER should be reduced gradually and eventually can be stopped under the supervision of a doctor or specialist. Suddenly stopping the medication may lead to recurrence of symptoms or irritability, anxiety, dizziness and tremors.
Q. Is Divaa-OD 125 Tablet ER a mood stabilizer?
Yes, Divaa-OD 125 Tablet ER can sometimes be used as a mood stabilizer. It is given in patients who experience rapid changes in their mood. It works by calming the hyperactivity of the brain during mood changes.
Q. Can Divaa-OD 125 Tablet ER cause weight gain?
Yes, Divaa-OD 125 Tablet ER may cause weight gain. The gain in weight could be due to an increase in hunger. Keep a check on your diet and exercise regularly to prevent any weight gain. If you are have concerns related to weight gain, consult your doctor.
Q. Does Divaa-OD 125 Tablet ER make you sleepy?
Yes, Divaa-OD 125 Tablet ER may make you feel sleepy. Avoid driving or other work that requires mental focus until you know how it affects you.
Q. Does Divaa-OD 125 Tablet ER cause hair loss?
Yes, Divaa-OD 125 Tablet ER may cause hair loss. However, it is only for a short time and is usually dose related. Please consult your doctor if the hair loss bothers you or persists for a longer duration.
Q. Can Divaa-OD 125 Tablet ER damage my liver?
Yes, Divaa-OD 125 Tablet ER can cause damage to the liver. The risk is more likely to occur during the first 6 months of starting the treatment with Divaa-OD 125 Tablet ER. Symptoms of liver damage may include nausea or vomiting, loss of appetite, stomach pain, dark coloured urine, facial swelling, yellowing of the skin or white of eyes. Therefore, it is important to have liver function tests done before starting the medicine and. Tests should be done periodically during the first 6 months of therapy, especially in those who are likely to be at risk and those with a prior history of liver disease.
Q. Can I take alcohol while I am taking Divaa-OD 125 Tablet ER?
Avoid alcohol consumption while you are on treatment with Divaa-OD 125 Tablet ER. Taking alcohol with this medicine may make you feel more drowsy, light headed or dizzy.
Q. What are the laboratory tests recommended prior to taking Divaa-OD 125 Tablet ER?
The doctor may suggest blood tests before starting the treatment with Divaa-OD 125 Tablet ER. The tests may include blood cell count, including platelet count, bleeding time and coagulation tests These tests are also advised to avoid any spontaneous bruising or bleeding. In addition to this, liver function tests are advised before therapy. It is recommended to periodically monitor liver function during the first 6 months of therapy, primarily in those who seem most at risk and those with a prior history of liver disease.
Q. What should be done if I start experiencing abdominal pain, nausea and anorexia?
If you experience acute severe abdominal pain along with nausea and vomiting, it may be due to pancreatitis. Immediately consult your doctor in case you experience these symptoms. Your doctor may get your levels of serum amylase checked. In case the test shows positive results for pancreatitis, the medication should be stopped immediately.
Q. How to check for overdose of Divaa-OD 125 Tablet ER?
Overdose of Divaa-OD 125 Tablet ER may cause headaches, blurred eyesight due to pupils of the eyes becoming smaller, lack of reflexes, confusion and tiredness. You may also experience weak or “floppy” muscles, fits (seizures), loss of consciousness, behavioral changes and breathing difficulties such as fast breathing, shortness of breath, or chest pain. Immediate medical assistance is required in case of overdose.
