Divagest 300mg Tablet SR (10'S)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Divagest 300mg Tablet SR is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).  It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well. The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration. 


Basic Information

Mechanism Of Action

Divagest 300mg Tablet SR is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.


Pharmacokinets

Progesterone is used by the sublingual route at dosages of 50 to 150 mg three to four times per day. A single 100 mg sublingual dose of Luteina has been found to reach mean peak progesterone levels of 13.5 ng/mL after 1 to 4 hours, with an elimination half-life of about 6 to 7 hours.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Divagest

Abdominal bloating

Hot flushes

Vaginal discharge

Urinary incontinence

Headache

Fatigue

Joint pain

Cough

Abnormal menstrual bleeding

Musculoskeletal (bone, muscle or joint) pain

Slurred speech

Pain behind eyes

Vertigo

Serve side effects of Divagest

Nausea

Sleepiness

Abdominal pain

Absence of menstrual periods

Itching

Change in body weight

Breast tenderness

Depression

Abnormal vaginal bleeding

Menstrual disorder

Edema (swelling)

Changes in cervical ectropion

Changes in cervical secretion

Cholestatic jaundice

Nipple discharge

Injection site reactions (pain, swelling, redness)

Red spots or bumps

Acne

Hair loss

Excessive hair growth on face

Anaphylactic reaction

Fever

Insomnia (difficulty in sleeping)

Contra Indications

breast cancer

diabetes

excessive fat in the blood

porphyria

overweight

depression

a migraine headache

a clot in the small veins that carry blood to or from the retina of the eye

high blood pressure

a heart attack

coronary artery disease

a clot in the lung

a stroke

obstruction of a blood vessel by a blood clot

thrombophlebitis, an inflamed vein due to a blood clot

blood clot in a deep vein of the extremities

at risk for formation of blood clots

liver problems

visible water retention

bedridden patient or one unable to move around freely

tobacco smoking

a liver tumor

Pregnancy Related Information

Divagest 300mg Tablet SR is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Divagest 300mg Tablet SR. Please consult your doctor.


Breast Feeding Related Information

Divagest 300mg Tablet SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Progesterone is used to help prevent changes in the uterus (womb) in women who are taking conjugated estrogens after menopause. It is also used to properly regulate the menstrual cycle and treat unusual stopping of menstrual periods (amenorrhea) in women who are still menstruating.

Interactions

bazedoxifene/conjugated estrogens.

conjugated estrogens.

conjugated estrogens, vaginal.

doxorubicin.

doxorubicin liposomal.

ruxolitinib.

Typical Dosage

Do not chew, crush or break it. Divagest 300mg Tablet SR is to be taken empty stomach.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Divagest 300mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Divagest 300mg Tablet SR is used in the treatment of female infertility and as a part of hormone replacement therapy.

It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.

It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).

It should be taken without food, preferably in the evening or at bedtime.

It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Divagest 300mg Tablet SR affects you.

It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Divagest 300mg Tablet SR is to be taken empty stomach.


FAQs

Q. Can you take Divagest 300mg Tablet SR every day?

Yes, Divagest 300mg Tablet SR can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Q. Does Divagest 300mg Tablet SR cause weight gain?

Yes, taking Divagest 300mg Tablet SR may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Divagest 300mg Tablet SR is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

Q. How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Divagest 300mg Tablet SR (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.