Manufacturer: West-Coast Pharmaceutical Works Ltd
Salt Composition : Ambroxol(30mg), Cetirizine(5mg), Dextromethorphan Hydrobromide(15mg), Phenylephrine(10mg)
Strip of 10 Tablet
(Inclusive of all taxes)
DMR-CC Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
DMR-CC Tablet is a combination of four medicines: Ambroxol, cetirizine, dextromethorphan and phenylephrine which relieve dry cough. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Cetirizine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.
Bioavailability of ambroxol administered orally is approximately 70–80%. The distribution half-life of ambroxol is 1.3 hours, metabolite is dibromoanthranilic acid (activity unspecified) and Elimination of ambroxol is biphasic, with an alpha half-life of 1.3 hours and a beta half-life of 8.8 hours.The Tmax of cetirizine is approximately 1.0 hour regardless of formulation. The pharmacokinetics of cetirizine have been found to increase linearly with dose across a range of 5 to 60 mg. Its Cmax following a single dose has been found to be 257 ng/mL for 10 mg and 580 ng/mL for 20 mg.Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood–brain barrier.Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration [1, 8]. It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of DMR-CC
Nausea
Vomiting
Stomach discomfort
Stomach pain
Upset stomach
Loss of appetite
Insomnia (difficulty in sleeping)
Skin rash
Itching
Sleepiness
Allergic reaction
If you are suffering from any of the following diseases, you should not take Cetirizine + Dextromethorphan + Phenylephrine + Ambroxol unless your doctor advises you to do so -
Kidney Disease
Liver Disease
Depression
Parkinson's Disease
Asthma
Heart Disease
Kidney Cancer
Liver Disease
Angina
Heart Disease
Coronary Artery Disease (CAD)
Hyperthyroidism
Diabetes
Glaucoma
Thyroid
Gastrointestinal Bleeding
Asthma
Smoking Addiction
DMR-CC Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with DMR-CC Tablet. Please consult your doctor.
Information regarding the use of DMR-CC Tablet during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Ambroxol+Cetirizine+Dextromethorphan Hydrobromide+Phenylephrine is used in the treatment of dry cough.Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Cetirizine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.
CETIRIZINE+DEXTROMETHORPHAN+AMBROXOL+PHENYLEPHRINE may interact with MAO inhibitor (isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine), anti-arrhythmic medications (amiodarone, propafenone, quinidine, and flecainide), opioid analgesics (codeine, tramadol, morphine, methadone), anti-anxiety medications (fluoxetine, paroxetine, sertraline), anti-fungal (terbinafine), blood thinners (warfarin, aspirin), anti-allergic drugs (diphenhydramine), anti-depressants (alprazolam, amitriptyline, amoxapine, clomipramine, doxepin), anticonvulsants (fosphenytoin, levetiracetam, phenytoin, valproic acid), HIV medications (lopinavir, ritonavir, saquinavir), antipsychotics (chlorpromazine, clozapine), diabetes medications (metformin, glimepiride, glipizide), and heart medications (digoxin).
Do not chew, crush or break it. DMR-CC Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of DMR-CC Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
DMR-CC Tablet is prescribed to get relief from a dry cough.
Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended. Use a proper measuring cup or spoon to measure the dosage.
If you are drowsy after taking DMR-CC Tablet, you should not drive or operate any machinery.
Inform your doctor if you have a history of stomach ulcers or asthma.
Inform your doctor if you are taking any other medications for e.g. anti-depressants.
Consult your doctor if you do not see any improvement and have a cough for more than 7 days.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DMR-CC Tablet may be taken with or without food, but it is better to take it at a fixed time.
