Manufacturer: Vhb Life Sciences Inc
Salt Composition : Dobutamine(250mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Doburan 250mg Injection is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly.
In clinical use, dobutamine has a rapid onset of action and a short half-life. It increases myocardial contractility, while the reflex reduction in sympathetic tone, in response to augmentation of stroke volume, leads to a decrease in total peripheral resistance.
plasma levels of dobutamine were monitored to determine the elimination half-life. The disappearance half-life of dobutamine was calculated to be 2.37 ± 0.7 min and the distribution volume was 0.202 ± 0.084 Llkg. The limited data suggest that the volume of distribution of dobutamine was related to the extent of edema.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doburan
High blood pressure
Insomnia (difficulty in sleeping)
The medication is contraindicated in patients with acute myocardial infarction, unstable angina, left main stem disease, severe hypertension, arrhythmias, acute myocarditis or pericarditis, hypokalemia and idiopathic hypertrophic sub-aortic stenosis.
Doburan 250mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Doburan 250mg Injection. Please consult your doctor.
Doburan 250mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Dobutamine is indicated in all paediatric age groups (from neonates to 18 years of age) as inotropic support in low cardiac output hypoperfusion states resulting from decompensated heart failure, following cardiac surgery, cardiomyopathies and in cardiogenic or septic shock.”
digitalis preparations
furosemide
spironolactone
lidocaine
nitroglycerin
isosorbide dinitrate
morphine
atropine
Kindly do not self administer.
Store below 30°C
If you miss a dose of Doburan 250mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
It is given into the vein as a drip by a healthcare professional.
Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
