Doflex 50mg Injection (3ml)

Manufacturer: Jagsonpal Pharmaceuticals Ltd

Salt Composition : Diclofenac(50mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Doflex 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Inform your doctor if you have any history of heart disease or stroke. Please consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.



Basic Information

Mechanism Of Action

As with all NSAIDs, diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency

Pharmacokinets

Diclofenac binds extensively to plasma albumin. The area under the plasma concentration-time curve (AUC) of diclofenac is proportional to the dose for oral doses between 25 to 150 mg. Substantial concentrations of drug are attained in synovial fluid, which is the proposed site of action for NSAIDs.


Side Effects

Limb pain

Injection site reactions (pain, swelling, redness)

Edema (swelling)

Nausea

Headache

Dizziness

Vomiting

Itching

Flatulence

Indigestion

Pain in extremities

Contra Indications

ischaemic heart disease.

peripheral arterial disease.

cerebrovascular disease.

congestive heart failure

Pregnancy Related Information

Doflex 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Doflex 50mg Injection. Please consult your doctor.


Breast Feeding Related Information

Doflex 50mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Diclofenac is indicated for use in the treatment of pain and inflammation from varying sources including inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as injury-related inflammation due to surgery and physical trauma.


Interactions

Some products that may interact with this drug include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as valsartan, losartan), corticosteroids (such as prednisone), cidofovir, lithium, methotrexate, "water pills" (diuretics such as furosemide).

Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

You have been prescribed Doflex 50mg Injection to relieve pain and inflammation.

Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.

It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.

Avoid consuming alcohol while taking Doflex 50mg Injection as it can cause excessive drowsiness and increase your risk of stomach problems.

Inform your doctor if you have a history of heart disease or stroke.

Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How should Doflex 50mg Injection injection be administered?

Doflex 50mg Injection injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.

Q. What is the most important information I need to know about Doflex 50mg Injection?

It is important to know that Doflex 50mg Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Doflex 50mg Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Q. Is Doflex 50mg Injection a good painkiller?

Doflex 50mg Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Q. Can Doflex 50mg Injection hurt your kidneys?

Long-term use and high doses of Doflex 50mg Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Q. Does Doflex 50mg Injection make you drowsy?

Doflex 50mg Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

Q. Can Doflex 50mg Injection be taken during pregnancy?

You should not take Doflex 50mg Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Doflex 50mg Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Doflex 50mg Injection during the first 6 months of pregnancy also. In some cases, Doflex 50mg Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Q. Does Doflex 50mg Injection get you high?

No, Doflex 50mg Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Q. Is Doflex 50mg Injection a narcotic?

No, Doflex 50mg Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.