Manufacturer: Mapra Laboratories Pvt Ltd
Salt Composition : Doxylamine(10mg), Vitamin B6(Pyridoxine),(10mg), Folic Acid(2.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dol B6 Forte 10mg/10mg/2.5mg Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.The most common side effects are dryness in the mouth, constipation, and lightheadedness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Dol B6 Forte 10mg/10mg/2.5mg Tablet is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic is also a form of vitamin B which provides essential nutrients.
The bioavailability of doxylamine is 24.7% for oral administration and 70.8% for intranasal administration. The Tmax of doxylamine is 1.5 to 2.5 hours. Its elimination half-life is 10 to 12 hours.Pyridoxine is rapidly metabolized in erythrocytes. 4-Pyridoxic acid and pyridoxine are secreted in renal tubulus, whereas pyridoxal is reabsorbed. Metabolism of vitamin B6 is altered in premature infants. Vitamin B6 supplements are of multipurpose use today.The pharmacokinetic profile of plasma FA after oral administration indicated an absorption rate-limited elimination, i.e., so called 'flip-flop' phenomenon. The bioavailability of FA was quite low after a high oral dose (F = 0.01), in contrast to a high value after intramuscular administration (F = 0.95).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dol B6 Forte
Sleepiness
Dizziness
Fatigue
Dryness in mouth
Constipation
If you are suffering from any of the following diseases, you should not take Doxylamine + Folic Acid + Vitamin B6 (Pyridoxine) unless your doctor advises you to do so -
Asthma
Peptic Ulcer
Bladder Infection
Liver Disease
Depression
Glaucoma
Pernicious Anemia
Kidney Disease
Drug Allergy
Kidney Disease
Drug Allergy
Seizures
Dol B6 Forte 10mg/10mg/2.5mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Caution is advised when consuming alcohol with Dol B6 Forte 10mg/10mg/2.5mg Tablet. Please consult your doctor.
Dol B6 Forte 10mg/10mg/2.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Larger doses or prolonged use of Dol B6 Forte 10mg/10mg/2.5mg Tablet may cause sleepiness and other effects in the baby
Use with caution
Below 9years: Contraindicated
Doxylamine+Vitamin B6 (Pyridoxine)+Folic Acid is used to prevent nausea and vomiting in pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic is also a form of vitamin B which provides essential nutrients.
DOXYLAMINE+FOLIC ACID+PYRIDOXINE may interact with blood thinners, monoamine oxidase inhibitors (selegiline, rasagiline, and tranylcypromine, etc.), sleeping pills (zolpidem, alprazolam, and triazolam, etc.), certain pain medicines (morphine and methadone, etc.), and cough or cold medicines (brompheniramine, chlorpheniramine, and diphenhydramine, etc.).
Do not chew, crush or break it. Dol B6 Forte 10mg/10mg/2.5mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Dol B6 Forte 10mg/10mg/2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Dol B6 Forte 10mg/10mg/2.5mg Tablet helps treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes.
Take it on an empty stomach with a glass of water.
It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
Do not take it with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dol B6 Forte 10mg/10mg/2.5mg Tablet is to be taken with food.
Q. What are the instructions for storage and disposal of Dol B6 Forte 10mg/10mg/2.5mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it at as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Dol B6 Forte 10mg/10mg/2.5mg Tablet can cause increased side effects. If you are experiencing increased severity of nausea or vomiting, which is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. Can the use of Dol B6 Forte 10mg/10mg/2.5mg Tablet cause drowsiness or sleepiness?
Yes, one of the common side effects of Dol B6 Forte 10mg/10mg/2.5mg Tablet is drowsiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking Dol B6 Forte 10mg/10mg/2.5mg Tablet. Severe drowsiness can happen or it can become worse and cause falls or accidents.
Q. Can the use of Dol B6 Forte 10mg/10mg/2.5mg Tablet cause dry mouth?
Yes, the use of Dol B6 Forte 10mg/10mg/2.5mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.
Q. Can a pregnant woman take Dol B6 Forte 10mg/10mg/2.5mg Tablet?
Yes, it is safe to take Dol B6 Forte 10mg/10mg/2.5mg Tablet in pregnant women. In fact, this medicine is used to treat nausea and vomiting in pregnant women. It is mainly recommended to those women whose symptoms have not improved after changing their diet or using other non-medicine treatments.
