Manufacturer: Vilco Laboratories Pvt Ltd
Salt Composition : Nimesulide(100mg), Paracetamol(500mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Doloflam Plus 100 mg/500 mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
Doloflam Plus 100 mg/500 mg Tablet is a combination of two medicines: Nimesulide and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Nimesulide is rapidly distributed and has an apparent volume of distribution ranging between 0.18 and 0.39 L/kg. It is extensively bound to albumin; the unbound fraction in plasma was 1%. The unbound fraction increased to 2 and 4% in patients with renal or hepatic insufficiency.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doloflam Plus
Nausea
Vomiting
Diarrhea
Increased liver enzymes
If you are allergic to nimesulide or paracetamol.
If you have problems with your liver or kidneys.
If you have flu, fever, chills and shivering.
If you have a history of liver damage induced by medicines like nimesulide.
If you had or have stomach bleeding, ulcer and inflammation of stomach lining.
If you have problems related to blood clotting, bleeding disorders.
If you have serious heart failure problems or heart-related disorders.
It should not be used in patients less than 12 years old, pregnant women or breastfeeding mothers.
Information regarding the use of Doloflam Plus 100 mg/500 mg Tablet during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Doloflam Plus 100 mg/500 mg Tablet.
Information regarding the use of Doloflam Plus 100 mg/500 mg Tablet during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
NIMESULIDE+PARACETAMOL is prescribed mainly to treat pain and get relief from discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps in treating pain by blocking the chemical messenger in the brain responsible for causing fever, pain and inflammation.
If you use other drugs or over the counter products at the same time, the effects of Doloflam Plus Tablet may change. This may increase your risk of side-effects or your medication may not work properly. Tell your doctor about all the medications, vitamins, and herbal supplements you use, so that your doctor can help you avoid or manage medication interactions. Doloflam Plus Tablet may interact with the following drugs and products:
Alcohol
Cyclosporine
Digitalis glycosides
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Leflunomide
Lithium
Methotrexate
Phenytoin
Do not chew, crush or break it. Doloflam Plus 100 mg/500 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Doloflam Plus 100 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doloflam Plus 100 mg/500 mg Tablet is to be taken with food.
Q. What is Doloflam Plus 100 mg/500 mg Tablet?
Doloflam Plus 100 mg/500 mg Tablet is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Q. Can I stop taking Doloflam Plus 100 mg/500 mg Tablet when my pain is relieved?
Doloflam Plus 100 mg/500 mg Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.
Q. Can the use of Doloflam Plus 100 mg/500 mg Tablet cause nausea and vomiting?
Yes, the use of Doloflam Plus 100 mg/500 mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. Are there any specific contraindications associated with the use of Doloflam Plus 100 mg/500 mg Tablet?
The use of Doloflam Plus 100 mg/500 mg Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Q. Can I take Doloflam Plus 100 mg/500 mg Tablet with Vitamin B-complex?
Yes, Doloflam Plus 100 mg/500 mg Tablet can be taken with Vitamin B-complex preparations. While Doloflam Plus 100 mg/500 mg Tablet helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.
Q. Does Doloflam Plus 100 mg/500 mg Tablet help in relieving stomach pain?
No, Doloflam Plus 100 mg/500 mg Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Q. Can the use of Doloflam Plus 100 mg/500 mg Tablet cause damage to the liver?
Doloflam Plus 100 mg/500 mg Tablet contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
Q. Is it safe to take a higher than the recommended dose of Doloflam Plus 100 mg/500 mg Tablet?
No, you should avoid taking a higher than the recommended dose of Doloflam Plus 100 mg/500 mg Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the recommended storage conditions for Doloflam Plus 100 mg/500 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
