Manufacturer: Lupin Ltd
Salt Composition : Piroxicam(20mg)
Dololup 20mg Tablet DT should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
Dololup 20mg Tablet DT is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.
Piroxicam is highly bound (approximately 99%) to plasma proteins and has a small distribution volume (approximately 10 l). Despite its high plasma binding, the drug readily penetrates into synovial fluid. Piroxicam has a long elimination half-life of about 50 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dololup
Vomiting
Stomach pain
Nausea
Headache
Dizziness
systemic mastocytosis.
anemia.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
alcoholism.
high blood pressure.
a heart attack.
chronic heart failure.
Dololup 20mg Tablet DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Dololup 20mg Tablet DT.
Dololup 20mg Tablet DT is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Piroxicam is indicated for symptomatic relief of osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis. Due to its safety profile (see sections 4.2, 4.3 and 4.4), piroxicam is not a first line option should an NSAID be indicated.
PIROXICAM may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol, atenolol, and lisinopril (used to treat high blood pressure), warfarin (used to prevent blood clotting), celecoxib, prednisone, and meloxicam (used to treat arthritis), sertraline (used to treat depression), and drugs used to treat high blood pressure and fluid retention.
Duration as advised by your doctor. Dissolve it in a glass of water before taking it. Dololup 20mg Tablet DT is to be taken with food.
Store below 30°C
If you miss a dose of Dololup 20mg Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Dololup 20mg Tablet DT helps relieve pain and swelling of various joints and muscles.
Take it with food to avoid stomach upset.
Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Dololup 20mg Tablet DT is to be taken with food.
Q. What is the difference between Dololup 20mg Tablet DT and diclofenac?
Both Dololup 20mg Tablet DT and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Dololup 20mg Tablet DT.
Q. What is the difference between Dololup 20mg Tablet DT and naproxen?
Both Dololup 20mg Tablet DT and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Dololup 20mg Tablet DT.
Q. What is the difference between Dololup 20mg Tablet DT and meloxicam?
Both Dololup 20mg Tablet DT and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Dololup 20mg Tablet DT.
Q. What is the difference between Dololup 20mg Tablet DT and ketoprofen?
Both Dololup 20mg Tablet DT and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Dololup 20mg Tablet DT. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Dololup 20mg Tablet DT and tramadol?
Dololup 20mg Tablet DT is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Dololup 20mg Tablet DT and nimesulide?
Both Dololup 20mg Tablet DT and nimesulide are pain killers. However, Dololup 20mg Tablet DT is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Dololup 20mg Tablet DT be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Dololup 20mg Tablet DT or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Dololup 20mg Tablet DT.
Q. Are Dololup 20mg Tablet DT and aspirin same?
No. Dololup 20mg Tablet DT and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Dololup 20mg Tablet DT be used along with dexamethasone?
No. Dololup 20mg Tablet DT should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Dololup 20mg Tablet DT be used with methocarbamol?
Yes. Methocarbamol can be used with Dololup 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Dololup 20mg Tablet DT be used along with paracetamol?
Yes. Paracetamol can be used with Dololup 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Dololup 20mg Tablet DT a NSAID?
Yes. Dololup 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Dololup 20mg Tablet DT a sulfa drug?
Dololup 20mg Tablet DT is a sulphur containing compound. Dololup 20mg Tablet DT can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Dololup 20mg Tablet DT a blood thinner?
No. Dololup 20mg Tablet DT is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Dololup 20mg Tablet DT a muscle relaxant?
No. Dololup 20mg Tablet DT is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Dololup 20mg Tablet DT a narcotic?
No. Dololup 20mg Tablet DT is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Dololup 20mg Tablet DT be used in hypertension?
No. Dololup 20mg Tablet DT is not a medication to control hypertension. It is important to note that Dololup 20mg Tablet DT decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Dololup 20mg Tablet DT.
Q. Can Dololup 20mg Tablet DT be used along with Losartan?
No. Dololup 20mg Tablet DT should not be combined with Losartan. It is important to note that Dololup 20mg Tablet DT decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dololup 20mg Tablet DT.
Q. Can Dololup 20mg Tablet DT be used with Lisinopril?
No. Dololup 20mg Tablet DT should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dololup 20mg Tablet DT.
Q. Can Dololup 20mg Tablet DT be used with calcium channel blocker?
Yes. Dololup 20mg Tablet DT can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Dololup 20mg Tablet DT be used with Tizanidine?
Yes, Dololup 20mg Tablet DT can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Dololup 20mg Tablet DT?
Yes. Dololup 20mg Tablet DT can be combined with beta-cyclodextrin. Research has shown that combining Dololup 20mg Tablet DT with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Dololup 20mg Tablet DT?
Yes. There are alternatives to Dololup 20mg Tablet DT. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Dololup 20mg Tablet DT?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Dololup 20mg Tablet DT be used in the treatment of allergy?
No. Dololup 20mg Tablet DT is not a drug to treat allergy. It is a pain killer.
Q. How long does Dololup 20mg Tablet DT work?
Dololup 20mg Tablet DT is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Dololup 20mg Tablet DT?
No. Dololup 20mg Tablet DT is not known to cause high. It is a non-narcotic painkiller.
Q. Can Dololup 20mg Tablet DT be used to treat menstrual cramp?
Dololup 20mg Tablet DT is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Dololup 20mg Tablet DT for a migraine?
Dololup 20mg Tablet DT is not approved for the treatment of migraine. Research studies have shown that Dololup 20mg Tablet DT is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Dololup 20mg Tablet DT effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Dololup 20mg Tablet DT as the cause of back pain can be different for different person.
Q. Is Dololup 20mg Tablet DT affective in gout management?
Yes. Dololup 20mg Tablet DT can be given for the treatment of acute gout. Research studies have shown Dololup 20mg Tablet DT to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Dololup 20mg Tablet DT?
Yes. You can donate blood when on Dololup 20mg Tablet DT. Do inform your doctor before donating blood.
Q. Can I use Dololup 20mg Tablet DT if I am a diabetic?
Dololup 20mg Tablet DT in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Dololup 20mg Tablet DT so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Dololup 20mg Tablet DT if I have a deranged renal function?
No. Dololup 20mg Tablet DT should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Dololup 20mg Tablet DT lead to skin reactions?
Yes. Dololup 20mg Tablet DT is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Dololup 20mg Tablet DT if I am pregnant?
No. Dololup 20mg Tablet DT should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Dololup 20mg Tablet DT if I have peptic ulcer disease?
No. Dololup 20mg Tablet DT is contraindicated in cases of active peptic ulcer disease. Dololup 20mg Tablet DT is known to cause gastric ulceration and bleeding.
Q. Can I use Dololup 20mg Tablet DT if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Dololup 20mg Tablet DT lead to difficulty in conception?
Yes. Dololup 20mg Tablet DT can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Dololup 20mg Tablet DT be used with diuretics?
No. Dololup 20mg Tablet DT should not be used with diuretics. Dololup 20mg Tablet DT reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Dololup 20mg Tablet DT be used with lithium?
No. Dololup 20mg Tablet DT should not be used with lithium. Dololup 20mg Tablet DT leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Dololup 20mg Tablet DT be used with warfarin?
No. Dololup 20mg Tablet DT should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Dololup 20mg Tablet DT?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Dololup 20mg Tablet DT?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Dololup 20mg Tablet DT?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
