Manufacturer: Ind Swift Laboratories Ltd
Salt Composition : Piroxicam(20mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Doloswift 20mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
Doloswift 20mg Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Piroxicam is highly bound (approximately 99%) to plasma proteins and has a small distribution volume (approximately 10 l). Despite its high plasma binding, the drug readily penetrates into synovial fluid. Piroxicam has a long elimination half-life of about 50 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doloswift
Injection site reactions (pain, swelling, redness)
Vomiting
Stomach pain
Nausea
Headache
Dizziness
systemic mastocytosis.
anemia.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
alcoholism.
high blood pressure.
a heart attack.
chronic heart failure.
Doloswift 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Caution is advised when consuming alcohol with Doloswift 20mg Injection. Please consult your doctor.
Doloswift 20mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Piroxicam is indicated for symptomatic relief of osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis. Due to its safety profile (see sections 4.2, 4.3 and 4.4), piroxicam is not a first line option should an NSAID be indicated.
PIROXICAM may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol, atenolol, and lisinopril (used to treat high blood pressure), warfarin (used to prevent blood clotting), celecoxib, prednisone, and meloxicam (used to treat arthritis), sertraline (used to treat depression), and drugs used to treat high blood pressure and fluid retention.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Doloswift 20mg Injection, consult your doctor.
Consult a doctor before taking any medicines.
Doloswift 20mg Injection helps relieve pain and swelling of various joints and muscles.
It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is the difference between Doloswift 20mg Injection and diclofenac?
Both Doloswift 20mg Injection and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Doloswift 20mg Injection.
Q. What is the difference between Doloswift 20mg Injection and naproxen?
Both Doloswift 20mg Injection and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Doloswift 20mg Injection.
Q. What is the difference between Doloswift 20mg Injection and meloxicam?
Both Doloswift 20mg Injection and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Doloswift 20mg Injection.
Q. What is the difference between Doloswift 20mg Injection and ketoprofen?
Both Doloswift 20mg Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Doloswift 20mg Injection. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Doloswift 20mg Injection and tramadol?
Doloswift 20mg Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Doloswift 20mg Injection and nimesulide?
Both Doloswift 20mg Injection and nimesulide are pain killers. However, Doloswift 20mg Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Doloswift 20mg Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Doloswift 20mg Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Doloswift 20mg Injection.
Q. Are Doloswift 20mg Injection and aspirin same?
No. Doloswift 20mg Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Doloswift 20mg Injection be used along with dexamethasone?
No. Doloswift 20mg Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Doloswift 20mg Injection be used with methocarbamol?
Yes. Methocarbamol can be used with Doloswift 20mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Doloswift 20mg Injection be used along with paracetamol?
Yes. Paracetamol can be used with Doloswift 20mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Doloswift 20mg Injection a NSAID?
Yes. Doloswift 20mg Injection is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Doloswift 20mg Injection a sulfa drug?
Doloswift 20mg Injection is a sulphur containing compound. Doloswift 20mg Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Doloswift 20mg Injection a blood thinner?
No. Doloswift 20mg Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Doloswift 20mg Injection a muscle relaxant?
No. Doloswift 20mg Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Doloswift 20mg Injection a narcotic?
No. Doloswift 20mg Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Doloswift 20mg Injection be used in hypertension?
No. Doloswift 20mg Injection is not a medication to control hypertension. It is important to note that Doloswift 20mg Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Doloswift 20mg Injection.
Q. Can Doloswift 20mg Injection be used along with Losartan?
No. Doloswift 20mg Injection should not be combined with Losartan. It is important to note that Doloswift 20mg Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloswift 20mg Injection.
Q. Can Doloswift 20mg Injection be used with Lisinopril?
No. Doloswift 20mg Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloswift 20mg Injection.
Q. Can Doloswift 20mg Injection be used with calcium channel blocker?
Yes. Doloswift 20mg Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Doloswift 20mg Injection be used with Tizanidine?
Yes, Doloswift 20mg Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Doloswift 20mg Injection?
Yes. Doloswift 20mg Injection can be combined with beta-cyclodextrin. Research has shown that combining Doloswift 20mg Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Doloswift 20mg Injection?
Yes. There are alternatives to Doloswift 20mg Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Doloswift 20mg Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Doloswift 20mg Injection be used in the treatment of allergy?
No. Doloswift 20mg Injection is not a drug to treat allergy. It is a pain killer.
Q. How long does Doloswift 20mg Injection work?
Doloswift 20mg Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Doloswift 20mg Injection?
No. Doloswift 20mg Injection is not known to cause high. It is a non-narcotic painkiller.
Q. Can Doloswift 20mg Injection be used to treat menstrual cramp?
Doloswift 20mg Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Doloswift 20mg Injection for a migraine?
Doloswift 20mg Injection is not approved for the treatment of migraine. Research studies have shown that Doloswift 20mg Injection is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Doloswift 20mg Injection effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Doloswift 20mg Injection as the cause of back pain can be different for different person.
Q. Is Doloswift 20mg Injection affective in gout management?
Yes. Doloswift 20mg Injection can be given for the treatment of acute gout. Research studies have shown Doloswift 20mg Injection to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Doloswift 20mg Injection?
Yes. You can donate blood when on Doloswift 20mg Injection. Do inform your doctor before donating blood.
Q. Can I use Doloswift 20mg Injection if I am a diabetic?
Doloswift 20mg Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Doloswift 20mg Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Doloswift 20mg Injection if I have a deranged renal function?
No. Doloswift 20mg Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Doloswift 20mg Injection lead to skin reactions?
Yes. Doloswift 20mg Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Doloswift 20mg Injection if I am pregnant?
No. Doloswift 20mg Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Doloswift 20mg Injection if I have peptic ulcer disease?
No. Doloswift 20mg Injection is contraindicated in cases of active peptic ulcer disease. Doloswift 20mg Injection is known to cause gastric ulceration and bleeding.
Q. Can I use Doloswift 20mg Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Doloswift 20mg Injection lead to difficulty in conception?
Yes. Doloswift 20mg Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Doloswift 20mg Injection be used with diuretics?
No. Doloswift 20mg Injection should not be used with diuretics. Doloswift 20mg Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Doloswift 20mg Injection be used with lithium?
No. Doloswift 20mg Injection should not be used with lithium. Doloswift 20mg Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Doloswift 20mg Injection be used with warfarin?
No. Doloswift 20mg Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Doloswift 20mg Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Doloswift 20mg Injection?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Doloswift 20mg Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
