Domi UP 2mg Injection (2ml)

Manufacturer: Lincoln Pharmaceuticals Ltd

Salt Composition : Ondansetron(2mg)

₹11.80

Vial of 2ml Injection

(Inclusive of all taxes)


Domi UP 2mg Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you appropriate dose depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections. 



Basic Information

Mechanism Of Action

Domi UP 2mg Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Pharmacokinets

Ondansetron is completely and rapidly absorbed from the gastrointestinal tract after oral administration, and does not accumulate with repeated oral administration. Owing to hepatic first-pass metabolism, its bioavailability is only about 60% compared with ondansetron administered by infusion over 15 minutes.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Domi UP

Injection site pain

Constipation

Diarrhea

Fatigue

Headache

Contra Indications

Hypersensitivity to Domi Up Injection is a contraindication. In addition, Domi Up Injection should not be used if you have the following conditions:

Gastric malignancy

Hypersensitivity

Impairment renal and hepatic functions

Lactation

Pregnancy

Pregnancy Related Information

Domi UP 2mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Domi UP 2mg Injection does not cause any harmful side effects.


Breast Feeding Related Information

Domi UP 2mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Ondansetron is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. initial and repeat courses of moderately emetogenic cancer chemotherapy.

Interactions

ONDANSETRON may cause a serious reaction when used with certain medicines like pain killers (acetaminophen, tramadol, ibuprofen), anti-anxiety (pregabalin, lorazepam), and antiparkinson medicine (apomorphine). 

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Domi UP 2mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed Domi UP 2mg Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.

It is given as an injection into veins or as drip under the supervision of a doctor.

Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How quickly does Domi UP 2mg Injection work?

Domi UP 2mg Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Domi UP 2mg Injection?

The most common side effects of Domi UP 2mg Injection are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Q. Is Domi UP 2mg Injection a steroid?

No, Domi UP 2mg Injection is an antiemetic and not a steroid. Domi UP 2mg Injection is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Q. Does Domi UP 2mg Injection work for seasickness?

No, Domi UP 2mg Injection does not work for seasickness. This is because Domi UP 2mg Injection has very little effect on the nausea associated with motion sickness.