Domi UP 4mg Tablet (10'S)

Manufacturer: Lincoln Pharmaceuticals Ltd

Salt Composition : Ondansetron(4mg)

₹52.00

Strip of 10 Tablet

(Inclusive of all taxes)


Domi UP 4mg Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.



Basic Information

Mechanism Of Action

Domi UP 4mg Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Pharmacokinets

Ondansetron is completely and rapidly absorbed from the gastrointestinal tract after oral administration, and does not accumulate with repeated oral administration. Owing to hepatic first-pass metabolism, its bioavailability is only about 60% compared with ondansetron administered by infusion over 15 minutes.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Domi UP

Constipation

Diarrhea

Fatigue

Headache

Contra Indications

Hypersensitivity to Domi Up Tablet is a contraindication. In addition, Domi Up Tablet should not be used if you have the following conditions:

Breast feeding

Kidney and liver function impairment

Pregnancy

stomach malignancy

hypersensitivity

Pregnancy Related Information

Domi UP 4mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Domi UP 4mg Tablet does not cause any harmful side effects.


Breast Feeding Related Information

Domi UP 4mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Ondansetron is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. initial and repeat courses of moderately emetogenic cancer chemotherapy.

Interactions

ONDANSETRON may cause a serious reaction when used with certain medicines like pain killers (acetaminophen, tramadol, ibuprofen), anti-anxiety (pregabalin, lorazepam), and antiparkinson medicine (apomorphine). 

Typical Dosage

Do not chew, crush or break it. Domi UP 4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Domi UP 4mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed Domi UP 4mg Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.

It is fast-acting and starts working within 30 minutes.

If you vomit within one hour of taking a dose, take another dose.

Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Domi UP 4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. How quickly does Domi UP 4mg Tablet work?

Domi UP 4mg Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Domi UP 4mg Tablet?

The most common side effects of Domi UP 4mg Tablet are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Q. When should you take Domi UP 4mg Tablet?

Domi UP 4mg Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Domi UP 4mg Tablet is taken before the start of your surgery, chemotherapy or radiation treatment.

Q. Is Domi UP 4mg Tablet a steroid?

No, Domi UP 4mg Tablet is an antiemetic and not a steroid. Domi UP 4mg Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Q. Does Domi UP 4mg Tablet work for seasickness?

No, Domi UP 4mg Tablet does not work for seasickness. This is because Domi UP 4mg Tablet has very little effect on the nausea associated with motion sickness.