Manufacturer: Lincoln Pharmaceuticals Ltd
Salt Composition : Ondansetron(2mg/5ml)
Bottle of 30ml Oral Solution
(Inclusive of all taxes)
Domi UP Oral Solution may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.
Domi UP Oral Solution blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older).
Ondansetron is completely and rapidly absorbed from the gastrointestinal tract after oral administration, and does not accumulate with repeated oral administration. Owing to hepatic first-pass metabolism, its bioavailability is only about 60% compared with ondansetron administered by infusion over 15 minutes.
Domi UP Oral Solution does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Domi UP
Constipation
Diarrhea
Fatigue
Headache
low amount of magnesium in the blood
low amount of potassium in the blood
extrapyramidal disease, a type of movement disorder
neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
serotonin syndrome, a type of disorder with high serotonin levels
a low supply of oxygen rich blood to the heart
torsades de pointes, a type of abnormal heart rhythm
slow heartbeat
prolonged QT interval on EKG
chronic heart failure
abnormal EKG with QT changes from birth
severe liver disease
PRESCRIBE THE CHILD'S DOCTOR
Use with caution
Below 9years: Contraindicated
Ondansetron is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. initial and repeat courses of moderately emetogenic cancer chemotherapy.
ONDANSETRON may cause a serious reaction when used with certain medicines like pain killers (acetaminophen, tramadol, ibuprofen), anti-anxiety (pregabalin, lorazepam), and antiparkinson medicine (apomorphine).
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Domi UP Oral Solution may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
Consult a doctor before taking any medicines.
Domi UP Oral Solution effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
It is fast-acting and starts working within 30 minutes.
Practice self-care measures:
Give plenty of fluids to your child to avoid dehydration
Avoid giving fried and spicy food or heavy meals to your child.
Ensure that your child eats slowly and in small proportions.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Domi UP Oral Solution may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Domi UP Oral Solution used for?
Domi UP Oral Solution is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Domi UP Oral Solution to your child to prevent vomiting post-procedure. Apart from this, Domi UP Oral Solution is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Domi UP Oral Solution to your child for a few days. Stick to the dose for best results.
Q. What if my child takes too much Domi UP Oral Solution?
Domi UP Oral Solution is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Domi UP Oral Solution can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
Q. How should Domi UP Oral Solution be stored?
Domi UP Oral Solution should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Q. Can other medicines be given at the same time as Domi UP Oral Solution?
Domi UP Oral Solution can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Domi UP Oral Solution. Also, check with your child’s doctor before giving any medicine to your child.
Q. In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
Q. My child is having a migraine and is on medication. Can I give Domi UP Oral Solution along with it?
Avoid combining Domi UP Oral Solution with such medicines because concomitant use of Domi UP Oral Solution with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
