Manufacturer: Cipla Ltd
Salt Composition : Domperidone(10mg), Paracetamol(500mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dompar 10 mg/500 mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Dompar 10 mg/500 mg Tablet is a combination of two medicines: Domperidone and Paracetamol / Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine.
The absorption of domperidone was very rapid, with mean peak plasma concentration (Cmax) values of 18.8, 15.0, and 20.7 ng/mL attained at 0.9, 1.2, and 0.6 hours after the administration of base tablet, maleate tablet, and solution, respectively. The mean elimination half-life (t1/2) ranged from 12.6 to 16.0 hours.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dompar
Dryness in mouth
Hypersensitivity to Dompar Tablet is a contraindication. In addition, Dompar Tablet should not be used if you have the following conditions:
Co-administration with potent CYP3A4 inhibitors
Concomitant use with medicines that prolong the QT interval
Congestive heart failure
Hepatic impairment
Hypersensitivity
Hypersensitivity to domperidone
Moderate or severe hepatic impairment
Patients with significant electrolyte disturbances
Presence of gastrointestinal haemorrhage
Presence of gastrointestinal mechanical obstruction or perforation
Dompar 10 mg/500 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Dompar 10 mg/500 mg Tablet.
Dompar 10 mg/500 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
DOMPERIDONE+PARACETAMOL is a combination medicine used for the symptomatic treatment of migraine, and any medical condition with concomitant nausea/vomiting and fever/pain.
If you use other drugs or over the counter products at the same time, the effects of Dompar Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Dompar Tablet may interact with the following drugs and products:
Alcohol
Amiodarone
Amprenavir
Antacids
Aprepitant
Atazanavir
Atropine
Clarithromycin
Diltiazem
Erythromycin
Do not chew, crush or break it. Dompar 10 mg/500 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Dompar 10 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Dompar 10 mg/500 mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Inform your doctor if you are taking any pain relief medicine.
Dompar 10 mg/500 mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
Some tips that may help avoid a migraine attack:
Have your meals at the same time every day.
Avoid bright lights and extreme temperatures.
Avoid loud music and noisy places.
Avoid chocolates, cheese, processed food, alcohol, and smoking.
Get sufficient sleep and avoid stress.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dompar 10 mg/500 mg Tablet is to be taken empty stomach.
Q. What is Dompar 10 mg/500 mg Tablet?
Dompar 10 mg/500 mg Tablet is a combination of two medicines: Domperidone and Paracetamol / Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol / Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
Q. Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Dompar 10 mg/500 mg Tablet can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. Can I get addicted to Dompar 10 mg/500 mg Tablet?
No, there is no report of any patient getting addicted to Dompar 10 mg/500 mg Tablet.
Q. Can the use of Dompar 10 mg/500 mg Tablet cause damage to liver?
Yes, Dompar 10 mg/500 mg Tablet can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
Q. What is the recommended storage condition for the Dompar 10 mg/500 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
