Manufacturer: BestoChem Formulations India Ltd
Salt Composition : Domperidone(30mg), Rabeprazole(20mg)
Strip of 10 Capsule
(Inclusive of all taxes)
Doran DSR 30 mg/20 mg Capsule is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Doran DSR 30 mg/20 mg Capsule is a combination of two medicines: Domperidone and Rabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach.
The absorption of domperidone was very rapid, with mean peak plasma concentration (Cmax) values of 18.8, 15.0, and 20.7 ng/mL attained at 0.9, 1.2, and 0.6 hours after the administration of base tablet, maleate tablet, and solution, respectively. The mean elimination half-life (t1/2) ranged from 12.6 to 16.0 hours.The pharmacokinetics of rabeprazole are characterized by high and consistent bioavailability, dose proportionality, extensive hepatic metabolism, and primarily urinary excretion of these metabolites. In addition, rabeprazole does not accumulate with repeated dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doran DSR
Diarrhea
Stomach pain
Dryness in mouth
Headache
Dizziness
Flatulence
Weakness
Flu-like symptoms
If you are allergic to Rabeprazole+Domperidone.
If you have problems with your heart, liver or kidney.
If you are suffering from bleeding in the digestive system.
If you are pregnant, planning to get pregnant or are breastfeeding.
If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
If you are taking any medications that may affect the contraction of the heart muscle (QT prolongation).
Doran DSR 30 mg/20 mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Doran DSR 30 mg/20 mg Capsule. Please consult your doctor.
Doran DSR 30 mg/20 mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Rabeprazole+Domperidone is used for the treatment of gastrointestinal reflux dis. It works by reducing the amount of acid produced in the stomach and improves motility in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Rabeprazole+Domperidone is available in the form of tablet, capsule.
DOMPERIDONE+RABEPRAZOLE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, fluconazole, posaconazole), anti-HIV drug (atazanavir, amprenavir, nelfinavir), antacid (magnesium hydroxide, aluminium hydroxide, cimetidine), iron supplements, antibiotics (clarithromycin, erythromycin, ampicillin, rifampicin), heart medicine (atropine, digoxin, amiodarone), blood pressure-lowering medicines (diltiazem), anti-cancer drug (methotrexate) and anti-nausea pills (aprepitant).
Duration as advised by your doctor. Doran DSR 30 mg/20 mg Capsule is to be taken empty stomach.
Store below 30°C
If you miss a dose of Doran DSR 30 mg/20 mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Doran DSR 30 mg/20 mg Capsule for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Take this medicine in the dose and duration as advised by your doctor. Doran DSR 30 mg/20 mg Capsule is to be taken empty stomach.
Q. What is Doran DSR 30 mg/20 mg Capsule?
Doran DSR 30 mg/20 mg Capsule is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
Q. What are the contraindications of Doran DSR 30 mg/20 mg Capsule?
The use of Doran DSR 30 mg/20 mg Capsule is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Q. Can the use of Doran DSR 30 mg/20 mg Capsule cause dry mouth?
Yes, the use of Doran DSR 30 mg/20 mg Capsule can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Q. Can the use of Doran DSR 30 mg/20 mg Capsule cause diarrhea?
Yes, the use of Doran DSR 30 mg/20 mg Capsule can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.
Q. What is the recommended storage condition for Doran DSR 30 mg/20 mg Capsule?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Is it safe to use Doran DSR 30 mg/20 mg Capsule?
Yes, Doran DSR 30 mg/20 mg Capsule is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. What is the best time to take Doran DSR 30 mg/20 mg Capsule?
It is best to take Doran DSR 30 mg/20 mg Capsule before the first meal of the day or on an empty stomach.
Q. Can the use of Doran DSR 30 mg/20 mg Capsule cause abnormal heartbeat?
Yes, the use of Doran DSR 30 mg/20 mg Capsule can increase the risk of developing irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
