Dorific 500mg Injection

Manufacturer: Gufic Bioscience Ltd

Salt Composition : Doripenem(500mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Dorific 500mg Injection is commonly used to treat seriously ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.



Basic Information

Mechanism Of Action

Dorific 500mg Injection is used to fight bacterial infections and prevent bacteria from growing. It acts by interfering with the bacterial protein synthesis which helps to treat the infection.

Pharmacokinets

The pharmacokinetic profile of doripenem is similar to that of imipenem and meropenem (5, 25, 32). In animal models, doripenem has the lowest potential among the carbapenems to cause seizure (43). Furthermore, no drug-related seizures were reported in phase 3 clinical trials of doripenem (32, 34).

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dorific

Headache

Nausea

Rash

Diarrhea

Inflammation of vein

Contra Indications

Doripenem is contraindicated in patients with known serious hypersensitivity to doripenem or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams.

Pregnancy Related Information

Dorific 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Dorific 500mg Injection does not cause any harmful side effects.


Breast Feeding Related Information

Dorific 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Doripenem for injection is indicated as a single agent for the treatment of complicated urinary tract infections, including pyelonephritis caused by Escherichia coli including cases with concurrent bacteremia, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Acinetobacter baumannii.

Interactions

bcg.

cholera vaccine, live.

divalproex sodium.

entecavir.

estradiol.

ethinyl estradiol.

indium oxyquinoline in-111.

mycophenolate mofetil.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Dorific 500mg Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Dorific 500mg Injection is an antibiotic that's usually only given in the hospital for serious infections.

It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes. In severe cases, it may be given slowly for 3 to 4 hours by intravenous infusion.

Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.

Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.

Your doctor may monitor your liver and kidney function while you are having treatment with this medication.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What is Dorific 500mg Injection used for?

Dorific 500mg Injection is used to fight bacterial infections and prevent bacteria from growing. It acts by interfering with the bacterial protein synthesis which helps to treat the infection. Dorific 500mg Injection is also helpful in the treatment of bacterial infections of the bladder, kidney and other parts of the urinary tract.

Q. Is Dorific 500mg Injection available over-the-counter?

No, Dorific 500mg Injection, just like other antibiotics, requires a valid prescription by a doctor to buy it. Therefore, it is advisable to take Dorific 500mg Injection only if prescribed by a doctor.

Q. How is Dorific 500mg Injection administered?

Dorific 500mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Dorific 500mg Injection.

Q. Does Dorific 500mg Injection cure flu?

No, antibiotics such as Dorific 500mg Injection will not work for flu or other viral infections. Using antibiotics when they are not needed may increase your risk of getting infection later, that resists antibiotic treatment. Consult your doctor if you have any doubts.

Q. What happens if I take too much of Dorific 500mg Injection?

If you have mistakenly taken too much of Dorific 500mg Injection, you may experience symptoms such as stomach ache, nausea and vomiting. You should consult your doctor immediately or rush to the emergency room in any nearby hospital if you have taken an overdose of Dorific 500mg Injection.

Q. Should I avoid some medicines while taking Dorific 500mg Injection?

Yes. There are some medicines that may reduce the effect of Dorific 500mg Injection, interact with Dorific 500mg Injection or cause serious side-effects when given at the same time. These medicines include Sodium Valproate, Ethinyl Estradiol and Live cholera vaccine. So, always inform and check with your doctor before taking Dorific 500mg Injection with other medications.

Q. How to store Dorific 500mg Injection?

Dorific 500mg Injection should be stored at around the room temperature (not more than 25°C) away from heat and sunlight. Do not freeze it and always keep it out of the reach and sight of the children.