Manufacturer: Three Dots Lifescience
Salt Composition : Amitriptyline(10mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Dottrip 10mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.
Dottrip 10mg Tablet contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).
Amitriptyline undergoes extensive hepatic presystemic elimination, and its systemic bioavailability ranges from 33% to 62% after oral administration [2]. A highly lipophilic compound, amitriptyline is widely distributed throughout the body and extensively bound to tissue and plasma proteins.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dottrip
Constipation
Dryness in mouth
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weight gain
Aggressive behavior
Nasal congestion (stuffy nose)
Sleepiness
Dizziness
Headache
Decreased libido
Nausea
Fatigue
Confusion
Tremors
Speech disorder
Palpitations
Taste change
Paresthesia (tingling or pricking sensation)
Abnormality of voluntary movements
Loss of accommodation
Atrioventricular block
Micturition disorders
Erectile dysfunction
Abnormal ECG
Decreased sodium level in blood
overactive thyroid gland
manic-depression
suicidal thoughts
alcoholism
wide-angle glaucoma
closed angle glaucoma
heart attack within the last 30 days
torsades de pointes, a type of abnormal heart rhythm
prolonged QT interval on EKG
abnormal heart rhythm
abnormal EKG with QT changes from birth
orthostatic hypotension, a form of low blood pressure
paralysis of the intestines
liver problems
enlarged prostate
seizures
an inability to completely empty the bladder
chronic idiopathic constipation
CYP2D6 poor metabolizer
Dottrip 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Dottrip 10mg Tablet.
Dottrip 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Amitriptyline is a medicine used for treating pain. You can take it: to treat nerve pain (neuralgia) and back pain. to help prevent migraine attacks.
AMITRIPTYLINE may have interactions with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma, neutropenia, kidney and liver problems.
Do not chew, crush or break it. Dottrip 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Dottrip 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It may take 4 to 6 weeks for Dottrip 10mg Tablet to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Dottrip 10mg Tablet as it may cause excessive sleepiness.
Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dottrip 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What other lifestyle changes should I make to get maximum benefit of Dottrip 10mg Tablet?
Antidepressants, including Dottrip 10mg Tablet, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of Dottrip 10mg Tablet and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.
Q. Is there anything I need to be careful about while on therapy with Dottrip 10mg Tablet?
Dottrip 10mg Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Q. Can the use of Dottrip 10mg Tablet affect my sex life?
Yes, Dottrip 10mg Tablet can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.
Q. I have been taking Dottrip 10mg Tablet for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?
You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, Dottrip 10mg Tablet takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking Dottrip 10mg Tablet, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.
Q. Can Dottrip 10mg Tablet cause urinary problems?
Yes, Dottrip 10mg Tablet can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may face difficulty in passing urine which can further lead to a urinary tract infection. Consult your doctor immediately if you develop these symptoms.
Q. If my pain is not relieved, can I take more than the recommended dose?
No, you should use Dottrip 10mg Tablet strictly as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because Dottrip 10mg Tablet takes about 2 weeks to show its effect, but it may take longer in some cases. The duration of treatment can differ from individual to individual. Consult your doctor if your symptoms are not relieved.
Q. Does Dottrip 10mg Tablet cause any effect on pregnancy or the newborn?
Do not take Dottrip 10mg Tablet during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.
Q. I have been prescribed Dottrip 10mg Tablet for pain. When will I start feeling better?
You may start feeling better after 2 weeks of starting Dottrip 10mg Tablet. However, it may take 4-6 weeks to see the full benefits of the medicine.
Q. Can I stop taking Dottrip 10mg Tablet when my pain is relieved?
No, do not stop taking Dottrip 10mg Tablet even if the pain is relieved. You should use Dottrip 10mg Tablet as advised by the doctor. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for the duration of the treatment since the dose of Dottrip 10mg Tablet needs to be reduced gradually.
Q. How long does Dottrip 10mg Tablet take to work?
You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Do not stop taking Dottrip 10mg Tablet after 1 or 2 weeks just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.
Q. How will Dottrip 10mg Tablet make me feel?
Antidepressants like Dottrip 10mg Tablet help to gradually lift your mood. You may notice that you sleep better and are less anxious. You may worry less about little things that used to bother you. Dottrip 10mg Tablet will not make you feel excessively or unusually happy. It will help you feel like yourself again.
