Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Docetaxel(80mg)
Doxaz 80mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The medicine works by interrupting the multiplication of cancer cells that results in cells being inactive and this leads to the death of the cancerous cells.
Docetaxel is widely distributed in tissues with a mean volume of distribution of 74 L/m2 after 100 mg/m2, every 3 weeks. The mean total body clearance after this schedule is approximately 22 L/h/m2, principally because of hepatic metabolism by the cytochrome P450 (CYP)3A4 system and biliary excretion into the faeces.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doxaz
Breathlessness
Constipation
Edema (swelling)
Infection
Loss of appetite
Muscle pain
Nail disorder
Pain
Weakness
a bad infection
anemia
decreased blood platelets
low levels of a type of white blood cell called neutrophils
a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
a disorder of the peripheral nerves that enable movement called peripheral motor neuropathy
macular swelling and degeneration of the eye
pericardial tamponade, a disorder of the heart
left ventricular heart failure
escape of fluid into the lungs
fluid in the lungs
stomatitis, a condition with painful swelling and sores inside the mouth
liver problems
visible water retention
fluid retention in the legs, feet, arms or hands
high amount of bilirubin in the blood
diarrhea
ascites
abnormal liver function tests
pregnancy
a patient who is producing milk and breastfeeding
lung tissue problem
Doxaz 80mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Doxaz 80mg Injection.
Doxaz 80mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Docetaxel injection is used to treat advanced or metastatic (cancer that has spread) breast cancer in patients who have previously received other cancer medicines that did not work well.
infections.
edema.
eye disorder.
hepatic dysfunction.
myelosuppression.
alcoholism.
paresthesia.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Doxaz 80mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Doxaz 80mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
Do not take Doxaz 80mg Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medication along with this medicine called Corticosteroids.
Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does Doxaz 80mg Injection cause weight gain?
Yes, Doxaz 80mg Injection may cause weight gain. It may occur due to fluid retention which may initially make your feet swell and then gradually it will spread to the whole body. Call your doctor immediately if you notice swelling of feet.
Q. How long do I have to take Doxaz 80mg Injection?
You should continue to take Doxaz 80mg Injection as long as your doctor advises you. The duration of treatment varies with the type of cancer you have and other factors like your response to treatment. You should usually receive your infusion once every 3 weeks.
Q. Can I drink alcohol while on Doxaz 80mg Injection?
Doxaz 80mg Injection injection contains alcohol because of which you may experience confusion, stumbling, becoming very sleepy, or feeling like you are drunk. This may impair your ability to drive or use machinery right after receiving it. Hence, you should avoid alcohol during Doxaz 80mg Injection therapy, as it may affect you adversely.
Q. What is Doxaz 80mg Injection used for?
Doxaz 80mg Injection is commonly used for breast cancer, certain types of lung cancer, prostate, stomach, and head and neck cancers. It works by restricting cells from growing and multiplying.
Q. Is Doxaz 80mg Injection available in pill form?
No, Doxaz 80mg Injection injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.
Q. What blood tests are required before administration of Doxaz 80mg Injection?
Your doctor will ask you to get blood tests every time you have a scheduled dose of Doxaz 80mg Injection. You may be asked to have blood tests, such as hemogram and liver function tests, to ensure that you have enough blood cells and that your liver is functioning well enough to receive Doxaz 80mg Injection. In case of white blood cells disturbances, you may experience associated fever or infections.
Q. Is hair loss caused by Doxaz 80mg Injection irreversible?
Hair loss is a common side effect of Doxaz 80mg Injection. Normal hair growth may resume after stopping Doxaz 80mg Injection. However, in some cases there is permanent hair loss. Consult your doctor if you have any concerns regarding hair loss.
Q. Why is dexamethasone used with Doxaz 80mg Injection?
Doxaz 80mg Injection may cause fluid retention (swelling in the hands, feet, ankles and legs) as well as severe hypersensitivity reactions. To control such possibilities from occurring all patients are given corticosteroids (dexamethasone) for 3 days starting 1 day prior to Doxaz 80mg Injection administration. In case of prostate cancer (metastatic castration-resistant), the recommended regimen is oral dexamethasone given at 12 hours, 3 hours, and 1 hour before the Doxaz 80mg Injection infusion.
Q. What type of drug is Doxaz 80mg Injection?
Doxaz 80mg Injection belongs to the group of anti-cancer medicines called taxoids. It works by stopping the growth and spread of cancer cells.
