Dpressin Nasal Spray (5ml)

Manufacturer: United Biotech Pvt Ltd

Salt Composition : Desmopressin(0.1mg/ml)


Dpressin Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril.



Basic Information

Mechanism Of Action

Dpressin Nasal Spray is a synthetic form of vasopressin (natural hormone that balances water). It is rapidly absorbed into the bloodstream through the inner surface of the nose. Once absorbed, it works by causing reabsorption of water from the kidneys which controls excessive thirst and urination in diabetes insipidus.

Pharmacokinets

The pharmacokinetic profile of desmopressin is biexponential. Terminal half-life was longer at night than in the daytime, but the difference is considered too small to be of clinical importance. The plasma levels given by the intravenous dose resulted in a duration of action of 12 h or more.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dpressin

Nasal discomfort

Nasopharyngitis (inflammation of the throat and nasal passages)

Nasal congestion (stuffy nose)

Sneezing

Back pain

Nosebleeds

Bronchitis (inflammation of the airways)

Dizziness

Contra Indications

low amount of sodium in the blood.

undue retention of water with sodium depletion.

cystic fibrosis.

high blood pressure.

coronary artery disease.

chronic heart failure.

moderate to severe kidney impairment.

psychogenic polydipsia.

Pregnancy Related Information

Dpressin Nasal Spray is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

No interaction found/established


Breast Feeding Related Information

Dpressin Nasal Spray is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Desmopressin is indicated for the treatment of polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. It was also newly approved for the treatment of mild classical hemophilia and von Willebrand's disease for minor surgeries.

Interactions

Tell your doctor before taking DESMOPRESSIN if you have a medical history of kidney disease, hypernatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. 

Typical Dosage

Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Dpressin Nasal Spray, skip it and continue with your normal schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

The right way to use the nasal spray:

Shake the bottle before using the medicine.

Clean your nose thoroughly before using the medicine.

Insert the bottle tip into one nostril and close the other nostril.

Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.

Breathe out gently through your mouth and repeat the same process for the other nostril.

Limit the amount of fluids you drink with this medication.

Do not share the bottle with anyone else so that you do not spread germs.

Use the Dpressin Nasal Spray within 4 weeks of opening it and discard the rest.

How To Use

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.


FAQs

Q. What precautions do I need to take while on Dpressin Nasal Spray?

Follow all the instructions given by your doctor strictly. Restrict water intake after taking Dpressin Nasal Spray as drinking too much water can lead to fluid overload, which is a serious side effect. Try not to swallow water while swimming.

Q. How long do I need to give Dpressin Nasal Spray to my child for bedwetting?

Dpressin Nasal Spray is usually prescribed for 3 months for bedwetting. After 3 months, your doctor will stop the medicine for a week to assess whether your child still needs Dpressin Nasal Spray or not.

Q. Does Dpressin Nasal Spray cure bed wetting?

No, Dpressin Nasal Spray does not cure bedwetting, but it helps control bedwetting. It works by replacing a hormone (vasopressin) that is normally produced in the body to help balance the amount of water and salt.

Q. Does Dpressin Nasal Spray make you gain weight?

No, Dpressin Nasal Spray itself does not cause weight gain. Dpressin Nasal Spray may cause fluid overload which may in turn cause weight gain. Fluid overload is a serious side effect and you should immediately contact your doctor if you experience headache, nausea, vomiting, restlessness, tiredness, loss of appetite, sleepiness, confusion and muscle cramps.

Q. Is Dpressin Nasal Spray a diuretic?

No, Dpressin Nasal Spray is not a diuretic. It is a hormone which helps lower urine output in patients with diabetes insipidus and helps control bedwetting in children. It works by reducing the amount of urine produced by the kidneys, thereby reducing the frequency of urination.